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Page 1
Plectasin, a fungal defensin, targets the bacterial cell wall precursor Lipid II.
Schneider T, Kruse T, Wimmer R, Wiedemann I, Sass V, Pag U, Jansen A, Nielsen AK, Mygind PH, Raventós DS, Neve S, Ravn B, Bonvin AM, De Maria L, Andersen AS, Gammelgaard LK, Sahl HG, Kristensen HH. Schneider T, et al. Among authors: raventos ds. Science. 2010 May 28;328(5982):1168-72. doi: 10.1126/science.1185723. Science. 2010. PMID: 20508130
Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus.
Mygind PH, Fischer RL, Schnorr KM, Hansen MT, Sönksen CP, Ludvigsen S, Raventós D, Buskov S, Christensen B, De Maria L, Taboureau O, Yaver D, Elvig-Jørgensen SG, Sørensen MV, Christensen BE, Kjaerulff S, Frimodt-Moller N, Lehrer RI, Zasloff M, Kristensen HH. Mygind PH, et al. Nature. 2005 Oct 13;437(7061):975-80. doi: 10.1038/nature04051. Nature. 2005. PMID: 16222292
Antimicrobial activity of the recombinant designer host defence peptide P-novispirin G10 in infected full-thickness wounds of porcine skin.
Jacobsen F, Mohammadi-Tabrisi A, Hirsch T, Mittler D, Mygind PH, Sonksen CP, Raventos D, Kristensen HH, Gatermann S, Lehnhardt M, Daigeler A, Steinau HU, Steinstraesser L. Jacobsen F, et al. J Antimicrob Chemother. 2007 Mar;59(3):493-8. doi: 10.1093/jac/dkl513. Epub 2007 Feb 8. J Antimicrob Chemother. 2007. PMID: 17289767