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Page 1
Assessing agonistic potential of a candidate therapeutic anti-IL21R antibody.
Guo Y, Hill AA, Ramsey RC, Immermann FW, Corcoran C, Young D, Lavallie ER, Ryan M, Bechard T, Pfeifer R, Warner G, Bologna M, Bloom L, O'Toole M. Guo Y, et al. Among authors: lavallie er. J Transl Med. 2010 May 26;8:50. doi: 10.1186/1479-5876-8-50. J Transl Med. 2010. PMID: 20504348 Free PMC article.
Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells.
DiBlasio-Smith EA, Arai M, Quinet EM, Evans MJ, Kornaga T, Basso MD, Chen L, Feingold I, Halpern AR, Liu QY, Nambi P, Savio D, Wang S, Mounts WM, Isler JA, Slager AM, Burczynski ME, Dorner AJ, LaVallie ER. DiBlasio-Smith EA, et al. Among authors: lavallie er. J Transl Med. 2008 Oct 16;6:59. doi: 10.1186/1479-5876-6-59. J Transl Med. 2008. PMID: 18925943 Free PMC article. Clinical Trial.
Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors.
Root AR, Guntas G, Katragadda M, Apgar JR, Narula J, Chang CS, Hanscom S, McKenna M, Wade J, Meade C, Ma W, Guo Y, Liu Y, Duan W, Hendershot C, King AC, Zhang Y, Sousa E, Tam A, Benard S, Yang H, Kelleher K, Jin F, Piche-Nicholas N, Keating SE, Narciandi F, Lawrence-Henderson R, Arai M, Stochaj WR, Svenson K, Mosyak L, Lam K, Francis C, Marquette K, Wroblewska L, Zhu HL, Sheehan AD, LaVallie ER, D'Antona AM, Betts A, King L, Rosfjord E, Cunningham O, Lin L, Sapra P, Tchistiakova L, Mathur D, Bloom L. Root AR, et al. Among authors: lavallie er. MAbs. 2021 Jan-Dec;13(1):1850395. doi: 10.1080/19420862.2020.1850395. MAbs. 2021. PMID: 33459147 Free PMC article.
Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer.
Root AR, Cao W, Li B, LaPan P, Meade C, Sanford J, Jin M, O'Sullivan C, Cummins E, Lambert M, Sheehan AD, Ma W, Gatto S, Kerns K, Lam K, D'Antona AM, Zhu L, Brady WA, Benard S, King A, He T, Racie L, Arai M, Barrett D, Stochaj W, LaVallie ER, Apgar JR, Svenson K, Mosyak L, Yang Y, Chichili GR, Liu L, Li H, Burke S, Johnson S, Alderson R, Finlay WJJ, Lin L, Olland S, Somers W, Bonvini E, Gerber HP, May C, Moore PA, Tchistiakova L, Bloom L. Root AR, et al. Among authors: lavallie er. Antibodies (Basel). 2016 Mar 4;5(1):6. doi: 10.3390/antib5010006. Antibodies (Basel). 2016. PMID: 31557987 Free PMC article.
Protein kinase Czeta is up-regulated in osteoarthritic cartilage and is required for activation of NF-kappaB by tumor necrosis factor and interleukin-1 in articular chondrocytes.
LaVallie ER, Chockalingam PS, Collins-Racie LA, Freeman BA, Keohan CC, Leitges M, Dorner AJ, Morris EA, Majumdar MK, Arai M. LaVallie ER, et al. J Biol Chem. 2006 Aug 25;281(34):24124-37. doi: 10.1074/jbc.M601905200. Epub 2006 Jun 23. J Biol Chem. 2006. PMID: 16798739 Free article.
An ultra-specific avian antibody to phosphorylated tau protein reveals a unique mechanism for phosphoepitope recognition.
Shih HH, Tu C, Cao W, Klein A, Ramsey R, Fennell BJ, Lambert M, Ní Shúilleabháin D, Autin B, Kouranova E, Laxmanan S, Braithwaite S, Wu L, Ait-Zahra M, Milici AJ, Dumin JA, LaVallie ER, Arai M, Corcoran C, Paulsen JE, Gill D, Cunningham O, Bard J, Mosyak L, Finlay WJ. Shih HH, et al. Among authors: lavallie er. J Biol Chem. 2012 Dec 28;287(53):44425-34. doi: 10.1074/jbc.M112.415935. Epub 2012 Nov 12. J Biol Chem. 2012. PMID: 23148212 Free PMC article.
Global analysis of nuclear receptor expression and dysregulation in human osteoarthritic articular cartilage: reduced LXR signaling contributes to catabolic metabolism typical of osteoarthritis.
Collins-Racie LA, Yang Z, Arai M, Li N, Majumdar MK, Nagpal S, Mounts WM, Dorner AJ, Morris E, LaVallie ER. Collins-Racie LA, et al. Among authors: lavallie er. Osteoarthritis Cartilage. 2009 Jul;17(7):832-42. doi: 10.1016/j.joca.2008.12.011. Epub 2009 Jan 19. Osteoarthritis Cartilage. 2009. PMID: 19217805 Free article.
Effect of adenovirus-mediated overexpression of bovine ADAMTS-4 and human ADAMTS-5 in primary bovine articular chondrocyte pellet culture system.
Arai M, Anderson D, Kurdi Y, Annis-Freeman B, Shields K, Collins-Racie LA, Corcoran C, DiBlasio-Smith E, Pittman DD, Dorner AJ, Morris E, LaVallie ER. Arai M, et al. Among authors: lavallie er. Osteoarthritis Cartilage. 2004 Aug;12(8):599-613. doi: 10.1016/j.joca.2004.05.001. Osteoarthritis Cartilage. 2004. PMID: 15262240 Free article.
ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage.
Collins-Racie LA, Flannery CR, Zeng W, Corcoran C, Annis-Freeman B, Agostino MJ, Arai M, DiBlasio-Smith E, Dorner AJ, Georgiadis KE, Jin M, Tan XY, Morris EA, LaVallie ER. Collins-Racie LA, et al. Among authors: lavallie er. Matrix Biol. 2004 Jul;23(4):219-30. doi: 10.1016/j.matbio.2004.05.004. Matrix Biol. 2004. PMID: 15296936
62 results