Tomkinson AE - Search Results

1

Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states.

Cotner-Gohara E, Kim IK, Hammel M, Tainer JA, Tomkinson AE, Ellenberger T. Cotner-Gohara E, et al. Among authors: tomkinson ae. Biochemistry. 2010 Jul 27;49(29):6165-76. doi: 10.1021/bi100503w. Biochemistry. 2010. PMID: 20518483 Free PMC article.

2

DNA ligase I from Saccharomyces cerevisiae: physical and biochemical characterization of the CDC9 gene product.

Tomkinson AE, Tappe NJ, Friedberg EC. Tomkinson AE, et al. Biochemistry. 1992 Dec 1;31(47):11762-71. doi: 10.1021/bi00162a013. Biochemistry. 1992. PMID: 1445910

3

Human DNA ligase I completely encircles and partially unwinds nicked DNA.

Pascal JM, O'Brien PJ, Tomkinson AE, Ellenberger T. Pascal JM, et al. Among authors: tomkinson ae. Nature. 2004 Nov 25;432(7016):473-8. doi: 10.1038/nature03082. Nature. 2004. PMID: 15565146

4

DNA ligases: structure, reaction mechanism, and function.

Tomkinson AE, Vijayakumar S, Pascal JM, Ellenberger T. Tomkinson AE, et al. Chem Rev. 2006 Feb;106(2):687-99. doi: 10.1021/cr040498d. Chem Rev. 2006. PMID: 16464020 Review. No abstract available.

5

Human DNA ligases I, III, and IV-purification and new specific assays for these enzymes.

Chen X, Pascal J, Vijayakumar S, Wilson GM, Ellenberger T, Tomkinson AE. Chen X, et al. Among authors: tomkinson ae. Methods Enzymol. 2006;409:39-52. doi: 10.1016/S0076-6879(05)09003-8. Methods Enzymol. 2006. PMID: 16793394

6

A flexible interface between DNA ligase and PCNA supports conformational switching and efficient ligation of DNA.

Pascal JM, Tsodikov OV, Hura GL, Song W, Cotner EA, Classen S, Tomkinson AE, Tainer JA, Ellenberger T. Pascal JM, et al. Among authors: tomkinson ae. Mol Cell. 2006 Oct 20;24(2):279-91. doi: 10.1016/j.molcel.2006.08.015. Mol Cell. 2006. PMID: 17052461 Free article.

7

The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase.

Vijayakumar S, Chapados BR, Schmidt KH, Kolodner RD, Tainer JA, Tomkinson AE. Vijayakumar S, et al. Among authors: tomkinson ae. Nucleic Acids Res. 2007;35(5):1624-37. doi: 10.1093/nar/gkm006. Epub 2007 Feb 18. Nucleic Acids Res. 2007. PMID: 17308348 Free PMC article.

8

Two DNA-binding and nick recognition modules in human DNA ligase III.

Cotner-Gohara E, Kim IK, Tomkinson AE, Ellenberger T. Cotner-Gohara E, et al. Among authors: tomkinson ae. J Biol Chem. 2008 Apr 18;283(16):10764-72. doi: 10.1074/jbc.M708175200. Epub 2008 Jan 30. J Biol Chem. 2008. PMID: 18238776 Free PMC article.

9

Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair.

Chen X, Zhong S, Zhu X, Dziegielewska B, Ellenberger T, Wilson GM, MacKerell AD Jr, Tomkinson AE. Chen X, et al. Among authors: tomkinson ae. Cancer Res. 2008 May 1;68(9):3169-77. doi: 10.1158/0008-5472.CAN-07-6636. Cancer Res. 2008. PMID: 18451142 Free PMC article.

10

Eukaryotic DNA ligases: structural and functional insights.

Ellenberger T, Tomkinson AE. Ellenberger T, et al. Among authors: tomkinson ae. Annu Rev Biochem. 2008;77:313-38. doi: 10.1146/annurev.biochem.77.061306.123941. Annu Rev Biochem. 2008. PMID: 18518823 Free PMC article. Review.

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