Smit AB - Search Results

1

Online fluorescence enhancement assay for the acetylcholine binding protein with parallel mass spectrometric identification.

Kool J, de Kloe GE, Bruyneel B, de Vlieger JS, Retra K, Wijtmans M, van Elk R, Smit AB, Leurs R, Lingeman H, de Esch IJ, Irth H. Kool J, et al. Among authors: smit ab. J Med Chem. 2010 Jun 24;53(12):4720-30. doi: 10.1021/jm100230k. J Med Chem. 2010. PMID: 20518527

2

The 2.7 A structure of AChBP, homologue of the ligand-binding domain of the nicotinic acetylcholine receptor.

Brejc K, van Dijk WJ, Smit AB, Sixma TK. Brejc K, et al. Among authors: smit ab. Novartis Found Symp. 2002;245:22-9; discussion 29-32, 165-8. Novartis Found Symp. 2002. PMID: 12027010 Review.

3

Granularin, a novel molluscan opsonin comprising a single vWF type C domain is up-regulated during parasitation.

Smit AB, De Jong-Brink M, Li KW, Sassen MM, Spijker S, Van Elk R, Buijs S, Van Minnen J, Van Kesteren RE. Smit AB, et al. FASEB J. 2004 May;18(7):845-7. doi: 10.1096/fj.03-0590fje. Epub 2004 Mar 19. FASEB J. 2004. PMID: 15033923

4

Crystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors.

Celie PH, Klaassen RV, van Rossum-Fikkert SE, van Elk R, van Nierop P, Smit AB, Sixma TK. Celie PH, et al. Among authors: smit ab. J Biol Chem. 2005 Jul 15;280(28):26457-66. doi: 10.1074/jbc.M414476200. Epub 2005 May 16. J Biol Chem. 2005. PMID: 15899893 Free article.

5

Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant.

Celie PH, Kasheverov IE, Mordvintsev DY, Hogg RC, van Nierop P, van Elk R, van Rossum-Fikkert SE, Zhmak MN, Bertrand D, Tsetlin V, Sixma TK, Smit AB. Celie PH, et al. Among authors: smit ab. Nat Struct Mol Biol. 2005 Jul;12(7):582-8. doi: 10.1038/nsmb951. Epub 2005 Jun 12. Nat Struct Mol Biol. 2005. PMID: 15951818

6

Alpha-conotoxin analogs with additional positive charge show increased selectivity towards Torpedo californica and some neuronal subtypes of nicotinic acetylcholine receptors.

Kasheverov IE, Zhmak MN, Vulfius CA, Gorbacheva EV, Mordvintsev DY, Utkin YN, van Elk R, Smit AB, Tsetlin VI. Kasheverov IE, et al. Among authors: smit ab. FEBS J. 2006 Oct;273(19):4470-81. doi: 10.1111/j.1742-4658.2006.05453.x. Epub 2006 Sep 5. FEBS J. 2006. PMID: 16956365 Free article.

7

Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis.

Ulens C, Akdemir A, Jongejan A, van Elk R, Bertrand S, Perrakis A, Leurs R, Smit AB, Sixma TK, Bertrand D, de Esch IJ. Ulens C, et al. Among authors: smit ab. J Med Chem. 2009 Apr 23;52(8):2372-83. doi: 10.1021/jm801400g. J Med Chem. 2009. PMID: 19331415

8

Development of surface plasmon resonance biosensor assays for primary and secondary screening of acetylcholine binding protein ligands.

Retra K, Geitmann M, Kool J, Smit AB, de Esch IJ, Danielson UH, Irth H. Retra K, et al. Among authors: smit ab. Anal Biochem. 2010 Dec 1;407(1):58-64. doi: 10.1016/j.ab.2010.06.021. Epub 2010 Jun 17. Anal Biochem. 2010. PMID: 20599657

9

Interaction kinetic and structural dynamic analysis of ligand binding to acetylcholine-binding protein.

Geitmann M, Retra K, de Kloe GE, Homan E, Smit AB, de Esch IJ, Danielson UH. Geitmann M, et al. Among authors: smit ab. Biochemistry. 2010 Sep 21;49(37):8143-54. doi: 10.1021/bi1006354. Biochemistry. 2010. PMID: 20701394

10

Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptor α7 ligands.

de Kloe GE, Retra K, Geitmann M, Källblad P, Nahar T, van Elk R, Smit AB, van Muijlwijk-Koezen JE, Leurs R, Irth H, Danielson UH, de Esch IJ. de Kloe GE, et al. Among authors: smit ab. J Med Chem. 2010 Oct 14;53(19):7192-201. doi: 10.1021/jm100834y. J Med Chem. 2010. PMID: 20828128

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