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The synthetic heat shock protein 90 (Hsp90) inhibitor EC141 induces degradation of Bcr-Abl p190 protein and apoptosis of Ph-positive acute lymphoblastic leukemia cells.
Tong WG, Estrov Z, Wang Y, O'Brien S, Faderl S, Harris DM, Van Pham Q, Hazan-Halevy I, Liu Z, Koch P, Kantarjian H, Keating MJ, Ferrajoli A. Tong WG, et al. Among authors: harris dm. Invest New Drugs. 2011 Dec;29(6):1206-12. doi: 10.1007/s10637-010-9465-8. Epub 2010 Jun 9. Invest New Drugs. 2011. PMID: 20533075 Free PMC article.
STAT-3 activates NF-kappaB in chronic lymphocytic leukemia cells.
Liu Z, Hazan-Halevy I, Harris DM, Li P, Ferrajoli A, Faderl S, Keating MJ, Estrov Z. Liu Z, et al. Among authors: harris dm. Mol Cancer Res. 2011 Apr;9(4):507-15. doi: 10.1158/1541-7786.MCR-10-0559. Epub 2011 Mar 1. Mol Cancer Res. 2011. PMID: 21364020 Free PMC article.
Aberrant LPL Expression, Driven by STAT3, Mediates Free Fatty Acid Metabolism in CLL Cells.
Rozovski U, Grgurevic S, Bueso-Ramos C, Harris DM, Li P, Liu Z, Wu JY, Jain P, Wierda W, Burger J, O'Brien S, Jain N, Ferrajoli A, Keating MJ, Estrov Z. Rozovski U, et al. Among authors: harris dm. Mol Cancer Res. 2015 May;13(5):944-53. doi: 10.1158/1541-7786.MCR-14-0412. Epub 2015 Mar 2. Mol Cancer Res. 2015. PMID: 25733697 Free PMC article.
Constitutive Phosphorylation of STAT3 by the CK2-BLNK-CD5 Complex.
Rozovski U, Harris DM, Li P, Liu Z, Jain P, Veletic I, Ferrajoli A, Burger J, O'Brien S, Bose P, Thompson P, Jain N, Wierda W, Keating MJ, Estrov Z. Rozovski U, et al. Among authors: harris dm. Mol Cancer Res. 2017 May;15(5):610-618. doi: 10.1158/1541-7786.MCR-16-0291. Epub 2017 Jan 27. Mol Cancer Res. 2017. PMID: 28130399 Free PMC article.
Ibrutinib inhibits free fatty acid metabolism in chronic lymphocytic leukemia.
Rozovski U, Harris DM, Li P, Liu Z, Jain P, Ferrajoli A, Burger J, Thompson P, Jain N, Wierda W, Keating MJ, Estrov Z. Rozovski U, et al. Among authors: harris dm. Leuk Lymphoma. 2018 Nov;59(11):2686-2691. doi: 10.1080/10428194.2018.1439167. Epub 2018 Feb 21. Leuk Lymphoma. 2018. PMID: 29465264 Free PMC article.
340 results