Luesch H - Search Results

1

A small-molecule inducer of the antioxidant response element.

Hur W, Sun Z, Jiang T, Mason DE, Peters EC, Zhang DD, Luesch H, Schultz PG, Gray NS. Hur W, et al. Among authors: luesch h. Chem Biol. 2010 May 28;17(5):537-47. doi: 10.1016/j.chembiol.2010.03.013. Chem Biol. 2010. PMID: 20534351

2

A genome-wide overexpression screen in yeast for small-molecule target identification.

Luesch H, Wu TY, Ren P, Gray NS, Schultz PG, Supek F. Luesch H, et al. Chem Biol. 2005 Jan;12(1):55-63. doi: 10.1016/j.chembiol.2004.10.015. Chem Biol. 2005. PMID: 15664515

3

A functional genomics approach to the mode of action of apratoxin A.

Luesch H, Chanda SK, Raya RM, DeJesus PD, Orth AP, Walker JR, Izpisúa Belmonte JC, Schultz PG. Luesch H, et al. Nat Chem Biol. 2006 Mar;2(3):158-67. doi: 10.1038/nchembio769. Epub 2006 Feb 12. Nat Chem Biol. 2006. PMID: 16474387

4

A genomic screen for activators of the antioxidant response element.

Liu Y, Kern JT, Walker JR, Johnson JA, Schultz PG, Luesch H. Liu Y, et al. Among authors: luesch h. Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5205-10. doi: 10.1073/pnas.0700898104. Epub 2007 Mar 12. Proc Natl Acad Sci U S A. 2007. PMID: 17360324 Free PMC article.

5

Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression.

Teo H, Ghosh S, Luesch H, Ghosh A, Wong ET, Malik N, Orth A, de Jesus P, Perry AS, Oliver JD, Tran NL, Speiser LJ, Wong M, Saez E, Schultz P, Chanda SK, Verma IM, Tergaonkar V. Teo H, et al. Among authors: luesch h. Nat Cell Biol. 2010 Aug;12(8):758-67. doi: 10.1038/ncb2080. Epub 2010 Jul 11. Nat Cell Biol. 2010. PMID: 20622870

6

In vitro and in vivo characterization of a tunable dual-reactivity probe of the Nrf2-ARE pathway.

Wang R, Mason DE, Choe KP, Lewin AS, Peters EC, Luesch H. Wang R, et al. Among authors: luesch h. ACS Chem Biol. 2013 Aug 16;8(8):1764-74. doi: 10.1021/cb4000103. Epub 2013 Jun 17. ACS Chem Biol. 2013. PMID: 23773140 Free PMC article.

7

Discovery of ML358, a Selective Small Molecule Inhibitor of the SKN-1 Pathway Involved in Drug Detoxification and Resistance in Nematodes.

Peddibhotla S, Fontaine P, Leung CK, Maloney P, Hershberger PM, Wang Y, Bousquet MS, Luesch H, Mangravita-Novo A, Pinkerton AB, Smith LH, Malany S, Choe K. Peddibhotla S, et al. Among authors: luesch h. ACS Chem Biol. 2015 Aug 21;10(8):1871-9. doi: 10.1021/acschembio.5b00304. Epub 2015 May 22. ACS Chem Biol. 2015. PMID: 25946346

8

Genome-wide overexpression screen for activators of antioxidant gene transcription.

Luesch H, Liu Y. Luesch H, et al. Methods Mol Biol. 2008;477:343-54. doi: 10.1007/978-1-60327-517-0_26. Methods Mol Biol. 2008. PMID: 19082959

9

Activation of the antioxidant response element by specific oxidized metabolites of linoleic acid.

Wang R, Kern JT, Goodfriend TL, Ball DL, Luesch H. Wang R, et al. Among authors: luesch h. Prostaglandins Leukot Essent Fatty Acids. 2009 Jul;81(1):53-9. doi: 10.1016/j.plefa.2009.04.008. Epub 2009 May 29. Prostaglandins Leukot Essent Fatty Acids. 2009. PMID: 19481916 Free PMC article.

10

Protection of human cultured cells against oxidative stress by Rhodiola rosea without activation of antioxidant defenses.

Schriner SE, Avanesian A, Liu Y, Luesch H, Jafari M. Schriner SE, et al. Among authors: luesch h. Free Radic Biol Med. 2009 Sep 1;47(5):577-84. doi: 10.1016/j.freeradbiomed.2009.05.025. Epub 2009 May 29. Free Radic Biol Med. 2009. PMID: 19486939 Free article.

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