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Page 1
Novel, Selective Inhibitors of USP7 Uncover Multiple Mechanisms of Antitumor Activity In Vitro and In Vivo.
Ohol YM, Sun MT, Cutler G, Leger PR, Hu DX, Biannic B, Rana P, Cho C, Jacobson S, Wong ST, Sanchez J, Shah N, Pookot D, Abraham B, Young K, Suthram S, Marshall LA, Bradford D, Kozon N, Han X, Okano A, Maung J, Colas C, Schwarz J, Wustrow D, Brockstedt DG, Kassner PD. Ohol YM, et al. Among authors: bradford d. Mol Cancer Ther. 2020 Oct;19(10):1970-1980. doi: 10.1158/1535-7163.MCT-20-0184. Epub 2020 Aug 11. Mol Cancer Ther. 2020. PMID: 32788207
Potent GCN2 Inhibitor Capable of Reversing MDSC-Driven T Cell Suppression Demonstrates In Vivo Efficacy as a Single Agent and in Combination with Anti-Angiogenesis Therapy.
Jackson JJ, Shibuya GM, Ravishankar B, Adusumilli L, Bradford D, Brockstedt DG, Bucher C, Bui M, Cho C, Colas C, Cutler G, Dukes A, Han X, Hu DX, Jacobson S, Kassner PD, Katibah GE, Ko MYM, Kolhatkar U, Leger PR, Ma A, Marshall L, Maung J, Ng AA, Okano A, Pookot D, Poon D, Ramana C, Reilly MK, Robles O, Schwarz JB, Shakhmin AA, Shunatona HP, Sreenivasan R, Tivitmahaisoon P, Xu M, Zaw T, Wustrow DJ, Zibinsky M. Jackson JJ, et al. Among authors: bradford d. J Med Chem. 2022 Oct 13;65(19):12895-12924. doi: 10.1021/acs.jmedchem.2c00736. Epub 2022 Sep 20. J Med Chem. 2022. PMID: 36127295
Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity.
Leger PR, Hu DX, Biannic B, Bui M, Han X, Karbarz E, Maung J, Okano A, Osipov M, Shibuya GM, Young K, Higgs C, Abraham B, Bradford D, Cho C, Colas C, Jacobson S, Ohol YM, Pookot D, Rana P, Sanchez J, Shah N, Sun M, Wong S, Brockstedt DG, Kassner PD, Schwarz JB, Wustrow DJ. Leger PR, et al. Among authors: bradford d. J Med Chem. 2020 May 28;63(10):5398-5420. doi: 10.1021/acs.jmedchem.0c00245. Epub 2020 May 6. J Med Chem. 2020. PMID: 32302140
Spontaneous cerebrovascular reactivity at rest in older adults with and without mild cognitive impairment and memory deficits.
Engstrom AC, Alitin JPM, Kapoor A, Dutt S, Lohman T, Sible IJ, Marshall AJ, Shenasa F, Gaubert A, Ferrer F, Nguyen A, Bradford DR, Rodgers K, Sordo L, Head E, Shao X, Wang DJJ, Nation DA. Engstrom AC, et al. Among authors: bradford dr. Alzheimers Dement. 2024 Nov 18. doi: 10.1002/alz.14396. Online ahead of print. Alzheimers Dement. 2024. PMID: 39555916
Racial biases in polygraphs and their legal implications.
Whittaker F, DeFalco A, Sanders SM, Perkins ER, Joyner KJ, Bradford DE. Whittaker F, et al. Among authors: bradford de. Nat Hum Behav. 2024 Nov 4. doi: 10.1038/s41562-024-02025-0. Online ahead of print. Nat Hum Behav. 2024. PMID: 39496770 No abstract available.
499 results