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Effects of the TP53 p.R249S mutant on proliferation and clonogenic properties in human hepatocellular carcinoma cell lines: interaction with hepatitis B virus X protein.
Gouas DA, Shi H, Hautefeuille AH, Ortiz-Cuaran SL, Legros PC, Szymanska KJ, Galy O, Egevad LA, Abedi-Ardekani B, Wiman KG, Hantz O, Caron de Fromentel C, Chemin IA, Hainaut PL. Gouas DA, et al. Among authors: wiman kg. Carcinogenesis. 2010 Aug;31(8):1475-82. doi: 10.1093/carcin/bgq118. Epub 2010 Jun 10. Carcinogenesis. 2010. PMID: 20538734
Mutant p53 targeting by the low molecular weight compound STIMA-1.
Zache N, Lambert JM, Rökaeus N, Shen J, Hainaut P, Bergman J, Wiman KG, Bykov VJ. Zache N, et al. Among authors: wiman kg. Mol Oncol. 2008 Jun;2(1):70-80. doi: 10.1016/j.molonc.2008.02.004. Epub 2008 Mar 7. Mol Oncol. 2008. PMID: 19383329 Free PMC article.
PRIMA-1 reactivates mutant p53 by covalent binding to the core domain.
Lambert JM, Gorzov P, Veprintsev DB, Söderqvist M, Segerbäck D, Bergman J, Fersht AR, Hainaut P, Wiman KG, Bykov VJ. Lambert JM, et al. Among authors: wiman kg. Cancer Cell. 2009 May 5;15(5):376-88. doi: 10.1016/j.ccr.2009.03.003. Cancer Cell. 2009. PMID: 19411067 Free article.
Mutant p53 rescue and modulation of p53 redox state.
Bykov VJ, Lambert JM, Hainaut P, Wiman KG. Bykov VJ, et al. Among authors: wiman kg. Cell Cycle. 2009 Aug 15;8(16):2509-17. doi: 10.4161/cc.8.16.9382. Epub 2009 Aug 29. Cell Cycle. 2009. PMID: 19633417 Review.
30 years and a long way into p53 research.
Hainaut P, Wiman KG. Hainaut P, et al. Among authors: wiman kg. Lancet Oncol. 2009 Sep;10(9):913-9. doi: 10.1016/S1470-2045(09)70198-6. Lancet Oncol. 2009. PMID: 19717093
191 results