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1,168 results

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Page 1
Discovery of orally available spirodiketopiperazine-based CCR5 antagonists.
Nishizawa R, Nishiyama T, Hisaichi K, Hirai K, Habashita H, Takaoka Y, Tada H, Sagawa K, Shibayama S, Maeda K, Mitsuya H, Nakai H, Fukushima D, Toda M. Nishizawa R, et al. Among authors: nakai h. Bioorg Med Chem. 2010 Jul 15;18(14):5208-23. doi: 10.1016/j.bmc.2010.05.057. Epub 2010 May 25. Bioorg Med Chem. 2010. PMID: 20542438 Free PMC article.
Design and synthesis of orally bioavailable inhibitors of inducible nitric oxide synthase. Part 1: synthesis and biological evaluation of dihydropyridin-2-imines.
Kawanaka Y, Kobayashi K, Kusuda S, Tatsumi T, Murota M, Nishiyama T, Hisaichi K, Fujii A, Hirai K, Naka M, Komeno M, Nakai H, Toda M. Kawanaka Y, et al. Among authors: nakai h. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2291-4. doi: 10.1016/s0960-894x(02)00455-9. Bioorg Med Chem Lett. 2002. PMID: 12161118
Design and synthesis of orally bioavailable inhibitors of inducible nitric oxide synthase. synthesis and biological evaluation of dihydropyridin-2(1H)-imines and 1,5,6,7-tetrahydro-2H-azepin-2-imines.
Kawanaka Y, Kobayashi K, Kusuda S, Tatsumi T, Murota M, Nishiyama T, Hisaichi K, Fujii A, Hirai K, Nishizaki M, Naka M, Komeno M, Nakai H, Toda M. Kawanaka Y, et al. Among authors: nakai h. Bioorg Med Chem. 2003 Mar 6;11(5):689-702. doi: 10.1016/s0968-0896(02)00540-0. Bioorg Med Chem. 2003. PMID: 12537998
Orally active PDE4 inhibitors with therapeutic potential.
Ochiai H, Ohtani T, Ishida A, Kishikawa K, Obata T, Nakai H, Toda M. Ochiai H, et al. Among authors: nakai h. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1323-7. doi: 10.1016/j.bmcl.2003.12.018. Bioorg Med Chem Lett. 2004. PMID: 14980691
Discovery of orally active prostaglandin D2 receptor antagonists.
Torisu K, Kobayashi K, Iwahashi M, Nakai Y, Onoda T, Nagase T, Sugimoto I, Okada Y, Matsumoto R, Nanbu F, Ohuchida S, Nakai H, Toda M. Torisu K, et al. Among authors: nakai y, nakai h. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4891-5. doi: 10.1016/j.bmcl.2004.07.039. Bioorg Med Chem Lett. 2004. PMID: 15341946
Discovery of new chemical leads for prostaglandin D2 receptor antagonists.
Torisu K, Kobayashi K, Iwahashi M, Egashira H, Nakai Y, Okada Y, Nanbu F, Ohuchida S, Nakai H, Toda M. Torisu K, et al. Among authors: nakai y, nakai h. Bioorg Med Chem Lett. 2004 Sep 6;14(17):4557-62. doi: 10.1016/j.bmcl.2004.06.006. Bioorg Med Chem Lett. 2004. PMID: 15357992
Discovery of a new chemical lead for a matrix metalloproteinase inhibitor.
Ikura M, Nakatani S, Yamamoto S, Habashita H, Sugiura T, Takahashi K, Ogawa K, Ohno H, Nakai H, Toda M. Ikura M, et al. Among authors: nakai h. Bioorg Med Chem. 2006 Jun 15;14(12):4241-52. doi: 10.1016/j.bmc.2006.01.059. Epub 2006 Feb 14. Bioorg Med Chem. 2006. PMID: 16481176
1,168 results