Marsh KC - Search Results

1

Liver transcriptomic changes associated with ritonavir-induced hyperlipidemia in sensitive and resistant strains of rats.

Yang Y, Dahly-Vernon AJ, Blomme EA, Lai-Zhang J, Kempf DJ, Marsh KC, Harrington YA, Nye SH, Evans DL, Roman RJ, Jacob HJ, Waring JF. Yang Y, et al. Among authors: marsh kc. Vet J. 2010 Jul;185(1):75-82. doi: 10.1016/j.tvjl.2010.04.017. Epub 2010 May 23. Vet J. 2010. PMID: 20547082

2

Identification of proteasome gene regulation in a rat model for HIV protease inhibitor-induced hyperlipidemia.

Waring JF, Ciurlionis R, Marsh K, Klein LL, Degoey DA, Randolph JT, Spear B, Kempf DJ. Waring JF, et al. Arch Toxicol. 2010 Apr;84(4):263-70. doi: 10.1007/s00204-010-0527-7. Epub 2010 Mar 6. Arch Toxicol. 2010. PMID: 20213465

3

Practical preclinical model for assessing the potential for unconjugated hyperbilirubinemia produced by human immunodeficiency virus protease inhibitors.

Kempf DJ, Waring JF, Morfitt DC, Werner P, Ebert B, Mitten M, Nguyen B, Randolph JT, DeGoey DA, Klein LL, Marsh K. Kempf DJ, et al. Antimicrob Agents Chemother. 2006 Feb;50(2):762-4. doi: 10.1128/AAC.50.2.762-764.2006. Antimicrob Agents Chemother. 2006. PMID: 16436740 Free PMC article.

4

Synthesis and activity of N-acyl azacyclic urea HIV-1 protease inhibitors with high potency against multiple drug resistant viral strains.

Zhao C, Sham HL, Sun M, Stoll VS, Stewart KD, Lin S, Mo H, Vasavanonda S, Saldivar A, Park C, McDonald EJ, Marsh KC, Klein LL, Kempf DJ, Norbeck DW. Zhao C, et al. Among authors: marsh kc. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5499-503. doi: 10.1016/j.bmcl.2005.08.093. Epub 2005 Oct 3. Bioorg Med Chem Lett. 2005. PMID: 16203141

5

Pharmacokinetic enhancement of the hepatitis C virus protease inhibitors VX-950 and SCH 503034 by co-dosing with ritonavir.

Kempf DJ, Klein C, Chen HJ, Klein LL, Yeung C, Randolph JT, Lau YY, Chovan LE, Guan Z, Hernandez L, Turner TM, Dandliker PJ, Marsh KC. Kempf DJ, et al. Among authors: marsh kc. Antivir Chem Chemother. 2007;18(3):163-7. doi: 10.1177/095632020701800306. Antivir Chem Chemother. 2007. PMID: 17626600 Free article.

6

Evaluation of the effects of serial phlebotomy on the transcriptome of major tissues and on the response to toxicants in rats.

Blomme EA, Ciurlionis R, Marsh KC, Waring JF, Yang Y. Blomme EA, et al. Among authors: marsh kc. Toxicol Lett. 2008 Jan 30;176(2):138-48. doi: 10.1016/j.toxlet.2007.09.014. Epub 2007 Oct 9. Toxicol Lett. 2008. PMID: 18164877

7

Water-soluble prodrugs of the human immunodeficiency virus protease inhibitors lopinavir and ritonavir.

DeGoey DA, Grampovnik DJ, Flosi WJ, Marsh KC, Wang XC, Klein LL, McDaniel KF, Liu Y, Long MA, Kati WM, Molla A, Kempf DJ. DeGoey DA, et al. Among authors: marsh kc. J Med Chem. 2009 May 14;52(9):2964-70. doi: 10.1021/jm900080g. J Med Chem. 2009. PMID: 19348416

8

Synthesis and evaluation of inhibitors of cytochrome P450 3A (CYP3A) for pharmacokinetic enhancement of drugs.

Flentge CA, Randolph JT, Huang PP, Klein LL, Marsh KC, Harlan JE, Kempf DJ. Flentge CA, et al. Among authors: marsh kc. Bioorg Med Chem Lett. 2009 Sep 15;19(18):5444-8. doi: 10.1016/j.bmcl.2009.07.118. Epub 2009 Jul 30. Bioorg Med Chem Lett. 2009. PMID: 19679477

9

N-vinylpyrrolidone dimer, a novel formulation excipient, causes hepatic and thyroid hypertrophy through the induction of hepatic microsomal enzymes in rats.

Yang Y, Ciurlionis R, Kowalkowski K, Marsh KC, Bracken WM, Blomme EA. Yang Y, et al. Among authors: marsh kc. Toxicol Lett. 2012 Jan 5;208(1):82-91. doi: 10.1016/j.toxlet.2011.10.012. Epub 2011 Oct 20. Toxicol Lett. 2012. PMID: 22037397

10

AhR activation underlies the CYP1A autoinduction by A-998679 in rats.

Liguori MJ, Lee CH, Liu H, Ciurlionis R, Ditewig AC, Doktor S, Andracki ME, Gagne GD, Waring JF, Marsh KC, Gopalakrishnan M, Blomme EA, Yang Y. Liguori MJ, et al. Among authors: marsh kc. Front Genet. 2012 Oct 26;3:213. doi: 10.3389/fgene.2012.00213. eCollection 2012. Front Genet. 2012. PMID: 23112805 Free PMC article.

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