Housley NA - Search Results

1

Rickettsia prowazekii uses an sn-glycerol-3-phosphate dehydrogenase and a novel dihydroxyacetone phosphate transport system to supply triose phosphate for phospholipid biosynthesis.

Frohlich KM, Roberts RA, Housley NA, Audia JP. Frohlich KM, et al. Among authors: housley na. J Bacteriol. 2010 Sep;192(17):4281-8. doi: 10.1128/JB.00443-10. Epub 2010 Jun 25. J Bacteriol. 2010. PMID: 20581209 Free PMC article.

2

The Rickettsia prowazekii ExoU homologue possesses phospholipase A1 (PLA1), PLA2, and lyso-PLA2 activities and can function in the absence of any eukaryotic cofactors in vitro.

Housley NA, Winkler HH, Audia JP. Housley NA, et al. J Bacteriol. 2011 Sep;193(18):4634-42. doi: 10.1128/JB.00141-11. Epub 2011 Jul 15. J Bacteriol. 2011. PMID: 21764940 Free PMC article.

3

Rickettsia prowazekii methionine aminopeptidase as a promising target for the development of antibacterial agents.

Helgren TR, Chen C, Wangtrakuldee P, Edwards TE, Staker BL, Abendroth J, Sankaran B, Housley NA, Myler PJ, Audia JP, Horn JR, Hagen TJ. Helgren TR, et al. Among authors: housley na. Bioorg Med Chem. 2017 Feb 1;25(3):813-824. doi: 10.1016/j.bmc.2016.11.013. Epub 2016 Nov 10. Bioorg Med Chem. 2017. PMID: 28089350 Free PMC article.

4

Caspase-1 Activation Protects Lung Endothelial Barrier Function during Infection-Induced Stress.

Alvarez DF, Housley N, Koloteva A, Zhou C, O'Donnell K, Audia JP. Alvarez DF, et al. Am J Respir Cell Mol Biol. 2016 Oct;55(4):500-510. doi: 10.1165/rcmb.2015-0386OC. Am J Respir Cell Mol Biol. 2016. PMID: 27119735 Free PMC article.

5

The Highly Selective Caspase-1 Inhibitor VX-765 Provides Additive Protection Against Myocardial Infarction in Rat Hearts When Combined With a Platelet Inhibitor.

Yang XM, Downey JM, Cohen MV, Housley NA, Alvarez DF, Audia JP. Yang XM, et al. Among authors: housley na. J Cardiovasc Pharmacol Ther. 2017 Nov;22(6):574-578. doi: 10.1177/1074248417702890. Epub 2017 Apr 12. J Cardiovasc Pharmacol Ther. 2017. PMID: 28399648 Free PMC article.

6

cAMP signaling primes lung endothelial cells to activate caspase-1 during Pseudomonas aeruginosa infection.

Renema P, Hardy KS, Housley N, Dunbar G, Annamdevula N, Britain A, Spadafora D, Leavesley S, Rich T, Audia JP, Alvarez DF. Renema P, et al. Am J Physiol Lung Cell Mol Physiol. 2020 May 1;318(5):L1074-L1083. doi: 10.1152/ajplung.00185.2019. Epub 2020 Mar 18. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32186399 Free PMC article.

7

In the absence of effector proteins, the Pseudomonas aeruginosa type three secretion system needle tip complex contributes to lung injury and systemic inflammatory responses.

Audia JP, Lindsey AS, Housley NA, Ochoa CR, Zhou C, Toba M, Oka M, Annamdevula NS, Fitzgerald MS, Frank DW, Alvarez DF. Audia JP, et al. Among authors: housley na. PLoS One. 2013 Nov 27;8(11):e81792. doi: 10.1371/journal.pone.0081792. eCollection 2013. PLoS One. 2013. PMID: 24312357 Free PMC article.

8

Caspase-1 inhibition by VX-765 administered at reperfusion in P2Y₁₂ receptor antagonist-treated rats provides long-term reduction in myocardial infarct size and preservation of ventricular function.

Audia JP, Yang XM, Crockett ES, Housley N, Haq EU, O'Donnell K, Cohen MV, Downey JM, Alvarez DF. Audia JP, et al. Basic Res Cardiol. 2018 Jul 10;113(5):32. doi: 10.1007/s00395-018-0692-z. Basic Res Cardiol. 2018. PMID: 29992382 Free PMC article.

9

Analysis of pulmonary vascular injury and repair during Pseudomonas aeruginosa infection-induced pneumonia and acute respiratory distress syndrome.

Lindsey AS, Sullivan LM, Housley NA, Koloteva A, King JA, Audia JP, Alvarez DF. Lindsey AS, et al. Among authors: housley na. Pulm Circ. 2019 Jan-Mar;9(1):2045894019826941. doi: 10.1177/2045894019826941. Pulm Circ. 2019. PMID: 30632898 Free PMC article.

10

The Pseudomonas aeruginosa Type III Secretion System Exoenzyme Effector ExoU Induces Mitochondrial Damage in a Murine Bone Marrow-Derived Macrophage Infection Model.

Hardy KS, Tuckey AN, Housley NA, Andrews J, Patel M, Al-Mehdi AB, Barrington RA, Cassel SL, Sutterwala FS, Audia JP. Hardy KS, et al. Among authors: housley na. Infect Immun. 2022 Mar 17;90(3):e0047021. doi: 10.1128/IAI.00470-21. Epub 2022 Feb 7. Infect Immun. 2022. PMID: 35130452 Free PMC article.

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