Mönkkönen H - Search Results

1

Aminobisphosphonate-pretreated dendritic cells trigger successful Vgamma9Vdelta2 T cell amplification for immunotherapy in advanced cancer patients.

Cabillic F, Toutirais O, Lavoué V, de La Pintière CT, Daniel P, Rioux-Leclerc N, Turlin B, Mönkkönen H, Mönkkönen J, Boudjema K, Catros V, Bouet-Toussaint F. Cabillic F, et al. Among authors: monkkonen h. Cancer Immunol Immunother. 2010 Nov;59(11):1611-9. doi: 10.1007/s00262-010-0887-0. Epub 2010 Jun 26. Cancer Immunol Immunother. 2010. PMID: 20582413 Free PMC article.

2

High phosphoantigen levels in bisphosphonate-treated human breast tumors promote Vgamma9Vdelta2 T-cell chemotaxis and cytotoxicity in vivo.

Benzaïd I, Mönkkönen H, Stresing V, Bonnelye E, Green J, Mönkkönen J, Touraine JL, Clézardin P. Benzaïd I, et al. Among authors: monkkonen h. Cancer Res. 2011 Jul 1;71(13):4562-72. doi: 10.1158/0008-5472.CAN-10-3862. Epub 2011 Jun 6. Cancer Res. 2011. PMID: 21646473

3

Upregulation of the mevalonate pathway by cholesterol depletion abolishes tolerance to N-bisphosphonate induced Vγ9Vδ2 T cell cytotoxicity in PC-3 prostate cancer cells.

Arkko S, Zlatev HP, Mönkkönen H, Räikkönen J, Benzaïd I, Clézardin P, Mönkkönen J, Määttä JA. Arkko S, et al. Among authors: monkkonen h. Cancer Lett. 2015 Feb 1;357(1):279-285. doi: 10.1016/j.canlet.2014.11.030. Epub 2014 Nov 21. Cancer Lett. 2015. PMID: 25444923

4

In vivo phosphoantigen levels in bisphosphonate-treated human breast tumors trigger Vγ9Vδ2 T-cell antitumor cytotoxicity through ICAM-1 engagement.

Benzaïd I, Mönkkönen H, Bonnelye E, Mönkkönen J, Clézardin P. Benzaïd I, et al. Among authors: monkkonen h. Clin Cancer Res. 2012 Nov 15;18(22):6249-59. doi: 10.1158/1078-0432.CCR-12-0918. Epub 2012 Oct 2. Clin Cancer Res. 2012. PMID: 23032740

5

Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP.

Roelofs AJ, Jauhiainen M, Mönkkönen H, Rogers MJ, Mönkkönen J, Thompson K. Roelofs AJ, et al. Among authors: monkkonen j, monkkonen h. Br J Haematol. 2009 Jan;144(2):245-50. doi: 10.1111/j.1365-2141.2008.07435.x. Epub 2008 Nov 7. Br J Haematol. 2009. PMID: 19016713 Free PMC article.

6

Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells.

Räikkönen J, Mönkkönen H, Auriola S, Mönkkönen J. Räikkönen J, et al. Among authors: monkkonen h. Biochem Pharmacol. 2010 Mar 1;79(5):777-83. doi: 10.1016/j.bcp.2009.10.003. Epub 2009 Oct 9. Biochem Pharmacol. 2010. PMID: 19819230

7

Activation of γδ T cells by bisphosphonates.

Thompson K, Roelofs AJ, Jauhiainen M, Mönkkönen H, Mönkkönen J, Rogers MJ. Thompson K, et al. Among authors: monkkonen h. Adv Exp Med Biol. 2010;658:11-20. doi: 10.1007/978-1-4419-1050-9_2. Adv Exp Med Biol. 2010. PMID: 19950011

8

Assessment of bisphosphonate activity in vitro.

Mitrofan LM, Auriola S, Mönkkönen H, Mönkkönen J. Mitrofan LM, et al. Among authors: monkkonen h. Curr Pharm Des. 2010;16(27):2970-80. doi: 10.2174/138161210793563644. Curr Pharm Des. 2010. PMID: 20722618 Review.

9

Zoledronic acid induces formation of a pro-apoptotic ATP analogue and isopentenyl pyrophosphate in osteoclasts in vivo and in MCF-7 cells in vitro.

Räikkönen J, Crockett JC, Rogers MJ, Mönkkönen H, Auriola S, Mönkkönen J. Räikkönen J, et al. Among authors: monkkonen j, monkkonen h. Br J Pharmacol. 2009 Jun;157(3):427-35. doi: 10.1111/j.1476-5381.2009.00160.x. Epub 2009 Apr 3. Br J Pharmacol. 2009. PMID: 19371349 Free PMC article.

10

Zoledronic acid-induced IPP/ApppI production in vivo.

Mönkkönen H, Ottewell PD, Kuokkanen J, Mönkkönen J, Auriola S, Holen I. Mönkkönen H, et al. Among authors: monkkonen j. Life Sci. 2007 Sep 8;81(13):1066-70. doi: 10.1016/j.lfs.2007.08.007. Epub 2007 Aug 17. Life Sci. 2007. PMID: 17850825

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