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Mechanisms of genomic instabilities underlying two common fragile-site-associated loci, PARK2 and DMD, in germ cell and cancer cell lines.
Mitsui J, Takahashi Y, Goto J, Tomiyama H, Ishikawa S, Yoshino H, Minami N, Smith DI, Lesage S, Aburatani H, Nishino I, Brice A, Hattori N, Tsuji S. Mitsui J, et al. Among authors: aburatani h. Am J Hum Genet. 2010 Jul 9;87(1):75-89. doi: 10.1016/j.ajhg.2010.06.006. Am J Hum Genet. 2010. PMID: 20598272 Free PMC article.
Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated Type I (slow twitch/red muscle) fiber genes, and impaired glycemic control.
Kamei Y, Miura S, Suzuki M, Kai Y, Mizukami J, Taniguchi T, Mochida K, Hata T, Matsuda J, Aburatani H, Nishino I, Ezaki O. Kamei Y, et al. Among authors: aburatani h. J Biol Chem. 2004 Sep 24;279(39):41114-23. doi: 10.1074/jbc.M400674200. Epub 2004 Jul 21. J Biol Chem. 2004. PMID: 15272020 Free article.
WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells.
Yamada T, Ishihara H, Tamura A, Takahashi R, Yamaguchi S, Takei D, Tokita A, Satake C, Tashiro F, Katagiri H, Aburatani H, Miyazaki J, Oka Y. Yamada T, et al. Among authors: aburatani h. Hum Mol Genet. 2006 May 15;15(10):1600-9. doi: 10.1093/hmg/ddl081. Epub 2006 Mar 28. Hum Mol Genet. 2006. PMID: 16571599
High-density oligonucleotide array with sub-kilobase resolution reveals breakpoint information of submicroscopic deletions in nevoid basal cell carcinoma syndrome.
Fujii K, Ishikawa S, Uchikawa H, Komura D, Shapero MH, Shen F, Hung J, Arai H, Tanaka Y, Sasaki K, Kohno Y, Yamada M, Jones KW, Aburatani H, Miyashita T. Fujii K, et al. Among authors: aburatani h. Hum Genet. 2007 Dec;122(5):459-66. doi: 10.1007/s00439-007-0419-y. Epub 2007 Aug 17. Hum Genet. 2007. PMID: 17703323
Genome-wide single-nucleotide polymorphism arrays in endometrial carcinomas associate extensive chromosomal instability with poor prognosis and unveil frequent chromosomal imbalances involved in the PI3-kinase pathway.
Murayama-Hosokawa S, Oda K, Nakagawa S, Ishikawa S, Yamamoto S, Shoji K, Ikeda Y, Uehara Y, Fukayama M, McCormick F, Yano T, Taketani Y, Aburatani H. Murayama-Hosokawa S, et al. Among authors: aburatani h. Oncogene. 2010 Apr 1;29(13):1897-908. doi: 10.1038/onc.2009.474. Epub 2010 Jan 11. Oncogene. 2010. PMID: 20062086
Tissue-specific demethylation in CpG-poor promoters during cellular differentiation.
Nagae G, Isagawa T, Shiraki N, Fujita T, Yamamoto S, Tsutsumi S, Nonaka A, Yoshiba S, Matsusaka K, Midorikawa Y, Ishikawa S, Soejima H, Fukayama M, Suemori H, Nakatsuji N, Kume S, Aburatani H. Nagae G, et al. Among authors: aburatani h. Hum Mol Genet. 2011 Jul 15;20(14):2710-21. doi: 10.1093/hmg/ddr170. Epub 2011 Apr 19. Hum Mol Genet. 2011. PMID: 21505077
661 results