Ren P - Search Results

1

A type-II kinase inhibitor capable of inhibiting the T315I "gatekeeper" mutant of Bcr-Abl.

Choi HG, Ren P, Adrian F, Sun F, Lee HS, Wang X, Ding Q, Zhang G, Xie Y, Zhang J, Liu Y, Tuntland T, Warmuth M, Manley PW, Mestan J, Gray NS, Sim T. Choi HG, et al. Among authors: ren p. J Med Chem. 2010 Aug 12;53(15):5439-48. doi: 10.1021/jm901808w. J Med Chem. 2010. PMID: 20604564 Free PMC article.

2

A general strategy for creating "inactive-conformation" abl inhibitors.

Okram B, Nagle A, Adrián FJ, Lee C, Ren P, Wang X, Sim T, Xie Y, Wang X, Xia G, Spraggon G, Warmuth M, Liu Y, Gray NS. Okram B, et al. Among authors: ren p. Chem Biol. 2006 Jul;13(7):779-86. doi: 10.1016/j.chembiol.2006.05.015. Chem Biol. 2006. PMID: 16873026

3

Discovery of pyrimidine benzimidazoles as Lck inhibitors: part I.

Zhang G, Ren P, Gray NS, Sim T, Liu Y, Wang X, Che J, Tian SS, Sandberg ML, Spalding TA, Romeo R, Iskandar M, Chow D, Martin Seidel H, Karanewsky DS, He Y. Zhang G, et al. Among authors: ren p. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5618-21. doi: 10.1016/j.bmcl.2008.08.104. Epub 2008 Aug 31. Bioorg Med Chem Lett. 2008. PMID: 18793846

4

Discovery of pyrimidine benzimidazoles as Src-family selective Lck inhibitors. Part II.

Zhang G, Ren P, Gray NS, Sim T, Wang X, Liu Y, Che J, Dong W, Tian SS, Sandberg ML, Spalding TA, Romeo R, Iskandar M, Wang Z, Seidel HM, Karanewsky DS, He Y. Zhang G, et al. Among authors: ren p. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6691-5. doi: 10.1016/j.bmcl.2009.09.123. Epub 2009 Oct 12. Bioorg Med Chem Lett. 2009. PMID: 19854052

5

A genome-wide overexpression screen in yeast for small-molecule target identification.

Luesch H, Wu TY, Ren P, Gray NS, Schultz PG, Supek F. Luesch H, et al. Among authors: ren p. Chem Biol. 2005 Jan;12(1):55-63. doi: 10.1016/j.chembiol.2004.10.015. Chem Biol. 2005. PMID: 15664515

6

Synthesis of 2beta-acyl-3beta-(substituted naphthyl)-8-azabicyclo[3.2.1]octanes and their binding affinities at dopamine and serotonin transport sites.

Davies HM, Gilliatt V, Kuhn LA, Saikali E, Ren P, Hammond PS, Sexton T, Childers SR. Davies HM, et al. Among authors: ren p. J Med Chem. 2001 May 10;44(10):1509-15. doi: 10.1021/jm000363+. J Med Chem. 2001. PMID: 11334561

7

Synthesis and monoamine transporter affinity of 3beta-(4-(2-pyrrolyl)phenyl)-8-azabicycl.

Davies HM, Ren P, Kong N, Sexton T, Childers SR. Davies HM, et al. Among authors: ren p. Bioorg Med Chem Lett. 2001 Feb 26;11(4):487-9. doi: 10.1016/s0960-894x(00)00701-0. Bioorg Med Chem Lett. 2001. PMID: 11229754

8

Synthesis of iodinated 3beta-aryltropanes with selective binding to either the dopamine or serotonin transporters.

Davies HM, Ren P, Kong NX, Sexton T, Childers SR. Davies HM, et al. Among authors: ren p. Bioorg Med Chem Lett. 2002 Mar 25;12(6):845-7. doi: 10.1016/s0960-894x(02)00048-3. Bioorg Med Chem Lett. 2002. PMID: 11958976

9

An exploratory study of type II [3 + 4] cycloadditions between vinylcarbenoids and dienes.

Davies HM, Calvo RL, Townsend RJ, Ren P, Churchill RM. Davies HM, et al. Among authors: ren p. J Org Chem. 2000 Jul 14;65(14):4261-8. doi: 10.1021/jo991959b. J Org Chem. 2000. PMID: 10891124

10

Catalytic asymmetric benzylic C-H activation by means of carbenoid-induced C-H insertions.

Davies HM, Jin Q, Ren P, Kovalevsky AY. Davies HM, et al. Among authors: ren p. J Org Chem. 2002 Jun 14;67(12):4165-9. doi: 10.1021/jo016351t. J Org Chem. 2002. PMID: 12054951

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