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Page 1
MDA-7/IL-24 as a cancer therapeutic: from bench to bedside.
Dent P, Yacoub A, Hamed HA, Park MA, Dash R, Bhutia SK, Sarkar D, Gupta P, Emdad L, Lebedeva IV, Sauane M, Su ZZ, Rahmani M, Broaddus WC, Young HF, Lesniak M, Grant S, Curiel DT, Fisher PB. Dent P, et al. Among authors: dash r. Anticancer Drugs. 2010 Sep;21(8):725-31. doi: 10.1097/CAD.0b013e32833cfbe1. Anticancer Drugs. 2010. PMID: 20613485 Free PMC article. Review.
Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant glioma.
Hamed HA, Yacoub A, Park MA, Eulitt PJ, Dash R, Sarkar D, Dmitriev IP, Lesniak MS, Shah K, Grant S, Curiel DT, Fisher PB, Dent P. Hamed HA, et al. Among authors: dash r. Mol Ther. 2010 Jun;18(6):1130-1142. doi: 10.1038/mt.2010.29. Epub 2010 Feb 23. Mol Ther. 2010. Retraction in: Mol Ther. 2024 Aug 29:S1525-0016(24)00542-2. doi: 10.1016/j.ymthe.2024.08.020. PMID: 20179672 Free PMC article. Retracted.
The development of MDA-7/IL-24 as a cancer therapeutic.
Dent P, Yacoub A, Hamed HA, Park MA, Dash R, Bhutia SK, Sarkar D, Wang XY, Gupta P, Emdad L, Lebedeva IV, Sauane M, Su ZZ, Rahmani M, Broaddus WC, Young HF, Lesniak MS, Grant S, Curiel DT, Fisher PB. Dent P, et al. Among authors: dash r. Pharmacol Ther. 2010 Nov;128(2):375-84. doi: 10.1016/j.pharmthera.2010.08.001. Epub 2010 Aug 21. Pharmacol Ther. 2010. PMID: 20732354 Free PMC article. Review.
Melanoma differentiation associated gene-7/interleukin-24 potently induces apoptosis in human myeloid leukemia cells through a process regulated by endoplasmic reticulum stress.
Rahmani M, Mayo M, Dash R, Sokhi UK, Dmitriev IP, Sarkar D, Dent P, Curiel DT, Fisher PB, Grant S. Rahmani M, et al. Among authors: dash r. Mol Pharmacol. 2010 Dec;78(6):1096-104. doi: 10.1124/mol.110.068007. Epub 2010 Sep 21. Mol Pharmacol. 2010. PMID: 20858700 Free PMC article.
mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.
Dash R, Bhutia SK, Azab B, Su ZZ, Quinn BA, Kegelmen TP, Das SK, Kim K, Lee SG, Park MA, Yacoub A, Rahmani M, Emdad L, Dmitriev IP, Wang XY, Sarkar D, Grant S, Dent P, Curiel DT, Fisher PB. Dash R, et al. Cytokine Growth Factor Rev. 2010 Oct;21(5):381-91. doi: 10.1016/j.cytogfr.2010.08.004. Cytokine Growth Factor Rev. 2010. PMID: 20926331 Free PMC article. Review.
A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.
Park MA, Hamed HA, Mitchell C, Cruickshanks N, Dash R, Allegood J, Dmitriev IP, Tye G, Ogretmen B, Spiegel S, Yacoub A, Grant S, Curiel DT, Fisher PB, Dent P. Park MA, et al. Among authors: dash r. Mol Pharmacol. 2011 Mar;79(3):368-80. doi: 10.1124/mol.110.069484. Epub 2010 Nov 30. Mol Pharmacol. 2011. PMID: 21119025 Free PMC article.
Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity.
Dash R, Azab B, Quinn BA, Shen X, Wang XY, Das SK, Rahmani M, Wei J, Hedvat M, Dent P, Dmitriev IP, Curiel DT, Grant S, Wu B, Stebbins JL, Pellecchia M, Reed JC, Sarkar D, Fisher PB. Dash R, et al. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8785-90. doi: 10.1073/pnas.1100769108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555592 Free PMC article.
748 results