Gilbert IH - Search Results

1

Selective delivery of 2-hydroxy APA to Trypanosoma brucei using the melamine motif.

Klee N, Wong PE, Baragaña B, Mazouni FE, Phillips MA, Barrett MP, Gilbert IH. Klee N, et al. Among authors: gilbert ih. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4364-6. doi: 10.1016/j.bmcl.2010.06.070. Epub 2010 Jun 17. Bioorg Med Chem Lett. 2010. PMID: 20615694 Free PMC article.

2

An approach to use an unusual adenosine transporter to selectively deliver polyamine analogues to trypanosomes.

Tye CK, Kasinathan G, Barrett MP, Brun R, Doyle VE, Fairlamb AH, Weaver R, Gilbert IH. Tye CK, et al. Among authors: gilbert ih. Bioorg Med Chem Lett. 1998 Apr 7;8(7):811-6. doi: 10.1016/s0960-894x(98)00095-x. Bioorg Med Chem Lett. 1998. PMID: 9871546

3

The structure-based design and synthesis of selective inhibitors of Trypanosoma cruzi dihydrofolate reductase.

Zuccotto F, Brun R, Gonzalez Pacanowska D, Ruiz Perez LM, Gilbert IH. Zuccotto F, et al. Among authors: gilbert ih. Bioorg Med Chem Lett. 1999 May 17;9(10):1463-8. doi: 10.1016/s0960-894x(99)00213-9. Bioorg Med Chem Lett. 1999. PMID: 10360757

4

Squalamine analogues as potential anti-trypanosomal and anti-leishmanial compounds.

Khabnadideh S, Tan CL, Croft SL, Kendrick H, Yardley V, Gilbert IH. Khabnadideh S, et al. Among authors: gilbert ih. Bioorg Med Chem Lett. 2000 Jun 5;10(11):1237-9. doi: 10.1016/s0960-894x(00)00196-7. Bioorg Med Chem Lett. 2000. PMID: 10866389

5

Novel inhibitors of Leishmanial dihydrofolate reductase.

Chowdhury SF, Di Lucrezia R, Guerrero RH, Brun R, Goodman J, Ruiz-Perez LM, Pacanowska DG, Gilbert IH. Chowdhury SF, et al. Among authors: gilbert ih. Bioorg Med Chem Lett. 2001 Apr 23;11(8):977-80. doi: 10.1016/s0960-894x(01)00089-0. Bioorg Med Chem Lett. 2001. PMID: 11327604

6

Selective inhibition of 6-phosphogluconate dehydrogenase from Trypanosoma brucei.

Bertelli M, El-Bastawissy E, Knaggs MH, Barrett MP, Hanau S, Gilbert IH. Bertelli M, et al. Among authors: gilbert ih. J Comput Aided Mol Des. 2001 May;15(5):465-75. doi: 10.1023/a:1011196508214. J Comput Aided Mol Des. 2001. PMID: 11394739

7

Synthesis and biological evaluation of s-triazine substituted polyamines as potential new anti-trypanosomal drugs.

Klenke B, Stewart M, Barrett MP, Brun R, Gilbert IH. Klenke B, et al. Among authors: gilbert ih. J Med Chem. 2001 Oct 11;44(21):3440-52. doi: 10.1021/jm010854+. J Med Chem. 2001. PMID: 11585449

8

Perspectives for new drugs against trypanosomiasis and leishmaniasis.

Barrett MP, Gilbert IH. Barrett MP, et al. Among authors: gilbert ih. Curr Top Med Chem. 2002 May;2(5):471-82. doi: 10.2174/1568026024607427. Curr Top Med Chem. 2002. PMID: 11966468 Review.

9

Synthesis and biological evaluation of substrate-based inhibitors of 6-phosphogluconate dehydrogenase as potential drugs against African trypanosomiasis.

Dardonville C, Rinaldi E, Hanau S, Barrett MP, Brun R, Gilbert IH. Dardonville C, et al. Among authors: gilbert ih. Bioorg Med Chem. 2003 Jul 17;11(14):3205-14. doi: 10.1016/s0968-0896(03)00191-3. Bioorg Med Chem. 2003. PMID: 12818683

10

Antiplasmodial activity of a series of 1,3,5-triazine-substituted polyamines.

Klenke B, Barrett MP, Brun R, Gilbert IH. Klenke B, et al. Among authors: gilbert ih. J Antimicrob Chemother. 2003 Aug;52(2):290-3. doi: 10.1093/jac/dkg307. Epub 2003 Jul 1. J Antimicrob Chemother. 2003. PMID: 12837742

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