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LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing.
James V, Zhang Y, Foxler DE, de Moor CH, Kong YW, Webb TM, Self TJ, Feng Y, Lagos D, Chu CY, Rana TM, Morley SJ, Longmore GD, Bushell M, Sharp TV. James V, et al. Among authors: chu cy. Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12499-504. doi: 10.1073/pnas.0914987107. Epub 2010 Jun 28. Proc Natl Acad Sci U S A. 2010. PMID: 20616046 Free PMC article.
Potent RNAi by short RNA triggers.
Chu CY, Rana TM. Chu CY, et al. RNA. 2008 Sep;14(9):1714-9. doi: 10.1261/rna.1161908. Epub 2008 Jul 24. RNA. 2008. PMID: 18658119 Free PMC article.
Target accessibility dictates the potency of human RISC.
Brown KM, Chu CY, Rana TM. Brown KM, et al. Among authors: chu cy. Nat Struct Mol Biol. 2005 May;12(5):469-70. doi: 10.1038/nsmb931. Epub 2005 Apr 24. Nat Struct Mol Biol. 2005. PMID: 15852021
Dissecting RNA-interference pathway with small molecules.
Chiu YL, Dinesh CU, Chu CY, Ali A, Brown KM, Cao H, Rana TM. Chiu YL, et al. Among authors: chu cy. Chem Biol. 2005 Jun;12(6):643-8. doi: 10.1016/j.chembiol.2005.04.016. Chem Biol. 2005. PMID: 15975509
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