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Safety and immunogenicity of HCV E1E2 vaccine adjuvanted with MF59 administered to healthy adults.
Frey SE, Houghton M, Coates S, Abrignani S, Chien D, Rosa D, Pileri P, Ray R, Di Bisceglie AM, Rinella P, Hill H, Wolff MC, Schultze V, Han JH, Scharschmidt B, Belshe RB. Frey SE, et al. Among authors: chien d. Vaccine. 2010 Aug 31;28(38):6367-73. doi: 10.1016/j.vaccine.2010.06.084. Epub 2010 Jul 7. Vaccine. 2010. PMID: 20619382 Free PMC article. Clinical Trial.
Induction of broad CD4+ and CD8+ T-cell responses and cross-neutralizing antibodies against hepatitis C virus by vaccination with Th1-adjuvanted polypeptides followed by defective alphaviral particles expressing envelope glycoproteins gpE1 and gpE2 and nonstructural proteins 3, 4, and 5.
Lin Y, Kwon T, Polo J, Zhu YF, Coates S, Crawford K, Dong C, Wininger M, Hall J, Selby M, Coit D, Medina-Selby A, McCoin C, Ng P, Drane D, Chien D, Han J, Vajdy M, Houghton M. Lin Y, et al. Among authors: chien d. J Virol. 2008 Aug;82(15):7492-503. doi: 10.1128/JVI.02743-07. Epub 2008 May 28. J Virol. 2008. PMID: 18508900 Free PMC article.
A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells.
Rosa D, Campagnoli S, Moretto C, Guenzi E, Cousens L, Chin M, Dong C, Weiner AJ, Lau JY, Choo QL, Chien D, Pileri P, Houghton M, Abrignani S. Rosa D, et al. Among authors: chien d. Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):1759-63. doi: 10.1073/pnas.93.5.1759. Proc Natl Acad Sci U S A. 1996. PMID: 8700831 Free PMC article.
Evaluation of hepatitis C virus glycoprotein E2 for vaccine design: an endoplasmic reticulum-retained recombinant protein is superior to secreted recombinant protein and DNA-based vaccine candidates.
Heile JM, Fong YL, Rosa D, Berger K, Saletti G, Campagnoli S, Bensi G, Capo S, Coates S, Crawford K, Dong C, Wininger M, Baker G, Cousens L, Chien D, Ng P, Archangel P, Grandi G, Houghton M, Abrignani S. Heile JM, et al. Among authors: chien d. J Virol. 2000 Aug;74(15):6885-92. doi: 10.1128/jvi.74.15.6885-6892.2000. J Virol. 2000. PMID: 10888628 Free PMC article.
Analysis of a successful immune response against hepatitis C virus.
Cooper S, Erickson AL, Adams EJ, Kansopon J, Weiner AJ, Chien DY, Houghton M, Parham P, Walker CM. Cooper S, et al. Among authors: chien dy. Immunity. 1999 Apr;10(4):439-49. doi: 10.1016/s1074-7613(00)80044-8. Immunity. 1999. PMID: 10229187 Free article.
236 results