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619 results

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Page 1
Identifying and characterizing chemical skin sensitizers without animal testing: Colipa's research and method development program.
Aeby P, Ashikaga T, Bessou-Touya S, Schepky A, Gerberick F, Kern P, Marrec-Fairley M, Maxwell G, Ovigne JM, Sakaguchi H, Reisinger K, Tailhardat M, Martinozzi-Teissier S, Winkler P. Aeby P, et al. Among authors: maxwell g. Toxicol In Vitro. 2010 Sep;24(6):1465-73. doi: 10.1016/j.tiv.2010.07.005. Epub 2010 Jul 17. Toxicol In Vitro. 2010. PMID: 20624454 Review.
Systematic evaluation of non-animal test methods for skin sensitisation safety assessment.
Reisinger K, Hoffmann S, Alépée N, Ashikaga T, Barroso J, Elcombe C, Gellatly N, Galbiati V, Gibbs S, Groux H, Hibatallah J, Keller D, Kern P, Klaric M, Kolle S, Kuehnl J, Lambrechts N, Lindstedt M, Millet M, Martinozzi-Teissier S, Natsch A, Petersohn D, Pike I, Sakaguchi H, Schepky A, Tailhardat M, Templier M, van Vliet E, Maxwell G. Reisinger K, et al. Among authors: maxwell g. Toxicol In Vitro. 2015 Feb;29(1):259-70. doi: 10.1016/j.tiv.2014.10.018. Toxicol In Vitro. 2015. PMID: 25448812 Free article.
Guiding principles for the implementation of non-animal safety assessment approaches for cosmetics: skin sensitisation.
Goebel C, Aeby P, Ade N, Alépée N, Aptula A, Araki D, Dufour E, Gilmour N, Hibatallah J, Keller D, Kern P, Kirst A, Marrec-Fairley M, Maxwell G, Rowland J, Safford B, Schellauf F, Schepky A, Seaman C, Teichert T, Tessier N, Teissier S, Weltzien HU, Winkler P, Scheel J. Goebel C, et al. Among authors: maxwell g. Regul Toxicol Pharmacol. 2012 Jun;63(1):40-52. doi: 10.1016/j.yrtph.2012.02.007. Epub 2012 Feb 21. Regul Toxicol Pharmacol. 2012. PMID: 22374415 Free article.
Categorization of chemicals according to their relative human skin sensitizing potency.
Basketter DA, Alépée N, Ashikaga T, Barroso J, Gilmour N, Goebel C, Hibatallah J, Hoffmann S, Kern P, Martinozzi-Teissier S, Maxwell G, Reisinger K, Sakaguchi H, Schepky A, Tailhardat M, Templier M. Basketter DA, et al. Among authors: maxwell g. Dermatitis. 2014 Jan-Feb;25(1):11-21. doi: 10.1097/DER.0000000000000003. Dermatitis. 2014. PMID: 24407057 Review.
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing.
Basketter DA, Clewell H, Kimber I, Rossi A, Blaauboer B, Burrier R, Daneshian M, Eskes C, Goldberg A, Hasiwa N, Hoffmann S, Jaworska J, Knudsen TB, Landsiedel R, Leist M, Locke P, Maxwell G, McKim J, McVey EA, Ouédraogo G, Patlewicz G, Pelkonen O, Roggen E, Rovida C, Ruhdel I, Schwarz M, Schepky A, Schoeters G, Skinner N, Trentz K, Turner M, Vanparys P, Yager J, Zurlo J, Hartung T. Basketter DA, et al. Among authors: maxwell g. ALTEX. 2012;29(1):3-91. doi: 10.14573/altex.2012.1.003. ALTEX. 2012. PMID: 22307314
Report of the EPAA-ECVAM workshop on the validation of Integrated Testing Strategies (ITS).
Kinsner-Ovaskainen A, Maxwell G, Kreysa J, Barroso J, Adriaens E, Alépée N, Berg N, Bremer S, Coecke S, Comenges JZ, Corvi R, Casati S, Dal Negro G, Marrec-Fairley M, Griesinger C, Halder M, Heisler E, Hirmann D, Kleensang A, Kopp-Schneider A, Lapenna S, Munn S, Prieto P, Schechtman L, Schultz T, Vidal JM, Worth A, Zuang V. Kinsner-Ovaskainen A, et al. Among authors: maxwell g. Altern Lab Anim. 2012 Jul;40(3):175-81. doi: 10.1177/026119291204000310. Altern Lab Anim. 2012. PMID: 22943518
Applying the skin sensitisation adverse outcome pathway (AOP) to quantitative risk assessment.
Maxwell G, MacKay C, Cubberley R, Davies M, Gellatly N, Glavin S, Gouin T, Jacquoilleot S, Moore C, Pendlington R, Saib O, Sheffield D, Stark R, Summerfield V. Maxwell G, et al. Toxicol In Vitro. 2014 Feb;28(1):8-12. doi: 10.1016/j.tiv.2013.10.013. Epub 2013 Oct 31. Toxicol In Vitro. 2014. PMID: 24184331
Informed by our previous efforts to model the induction of skin sensitisation (Maxwell and MacKay, 2008) we are now developing two mathematical models ('total haptenated protein' model and 'CD8(+) T cell response' model) that will be linked to provide predictions of the hu …
Informed by our previous efforts to model the induction of skin sensitisation (Maxwell and MacKay, 2008) we are now developing two ma …
619 results