Ungell AL - Search Results

1

Impact of input parameters on the prediction of hepatic plasma clearance using the well-stirred model.

Wan H, Bold P, Larsson LO, Ulander J, Peters S, Löfberg B, Ungell AL, Någård M, Llinàs A. Wan H, et al. Among authors: ungell al. Curr Drug Metab. 2010 Sep;11(7):583-94. doi: 10.2174/138920010792927334. Curr Drug Metab. 2010. PMID: 20629632

2

Physiologically based pharmacokinetic (PBPK) modeling and simulation: applications in lead optimization.

Peters SA, Ungell AL, Dolgos H. Peters SA, et al. Among authors: ungell al. Curr Opin Drug Discov Devel. 2009 Jul;12(4):509-18. Curr Opin Drug Discov Devel. 2009. PMID: 19562647 Review.

3

Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination.

Jones CR, Hatley OJ, Ungell AL, Hilgendorf C, Peters SA, Rostami-Hodjegan A. Jones CR, et al. Among authors: ungell al. AAPS J. 2016 May;18(3):589-604. doi: 10.1208/s12248-016-9889-y. Epub 2016 Mar 10. AAPS J. 2016. PMID: 26964996 Free PMC article. Review.

4

Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models.

Peters SA, Jones CR, Ungell AL, Hatley OJ. Peters SA, et al. Among authors: ungell al. Clin Pharmacokinet. 2016 Jun;55(6):673-96. doi: 10.1007/s40262-015-0351-6. Clin Pharmacokinet. 2016. PMID: 26895020 Free PMC article. Review.

5

Surface descriptors for protein-ligand affinity prediction.

Zamora I, Oprea T, Cruciani G, Pastor M, Ungell AL. Zamora I, et al. Among authors: ungell al. J Med Chem. 2003 Jan 2;46(1):25-33. doi: 10.1021/jm011051p. J Med Chem. 2003. PMID: 12502357

6

Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines.

Hilgendorf C, Ahlin G, Seithel A, Artursson P, Ungell AL, Karlsson J. Hilgendorf C, et al. Among authors: ungell al. Drug Metab Dispos. 2007 Aug;35(8):1333-40. doi: 10.1124/dmd.107.014902. Epub 2007 May 11. Drug Metab Dispos. 2007. PMID: 17496207

7

Comprehensive study on regional human intestinal permeability and prediction of fraction absorbed of drugs using the Ussing chamber technique.

Sjöberg Å, Lutz M, Tannergren C, Wingolf C, Borde A, Ungell AL. Sjöberg Å, et al. Among authors: ungell al. Eur J Pharm Sci. 2013 Jan 23;48(1-2):166-80. doi: 10.1016/j.ejps.2012.10.007. Epub 2012 Oct 26. Eur J Pharm Sci. 2013. PMID: 23103351

8

pH-dependent bidirectional transport of weakly basic drugs across Caco-2 monolayers: implications for drug-drug interactions.

Neuhoff S, Ungell AL, Zamora I, Artursson P. Neuhoff S, et al. Among authors: ungell al. Pharm Res. 2003 Aug;20(8):1141-8. doi: 10.1023/a:1025032511040. Pharm Res. 2003. PMID: 12948010

9

Impact of extracellular protein binding on passive and active drug transport across Caco-2 cells.

Neuhoff S, Artursson P, Zamora I, Ungell AL. Neuhoff S, et al. Among authors: ungell al. Pharm Res. 2006 Feb;23(2):350-9. doi: 10.1007/s11095-005-9304-3. Epub 2006 Jan 1. Pharm Res. 2006. PMID: 16388407

10

Characterization of THLE-cytochrome P450 (P450) cell lines: gene expression background and relationship to P450-enzyme activity.

Soltanpour Y, Hilgendorf C, Ahlström MM, Foster AJ, Kenna JG, Petersen A, Ungell AL. Soltanpour Y, et al. Among authors: ungell al. Drug Metab Dispos. 2012 Nov;40(11):2054-8. doi: 10.1124/dmd.112.045815. Epub 2012 Jul 30. Drug Metab Dispos. 2012. PMID: 22851615

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