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Haplotype analysis discriminates genetic risk for DR3-associated endocrine autoimmunity and helps define extreme risk for Addison's disease.
Baker PR, Baschal EE, Fain PR, Triolo TM, Nanduri P, Siebert JC, Armstrong TK, Babu SR, Rewers MJ, Gottlieb PA, Barker JM, Eisenbarth GS. Baker PR, et al. Among authors: fain pr. J Clin Endocrinol Metab. 2010 Oct;95(10):E263-70. doi: 10.1210/jc.2010-0508. Epub 2010 Jul 14. J Clin Endocrinol Metab. 2010. PMID: 20631027 Free PMC article.
Dominant suppression of Addison's disease associated with HLA-B15.
Baker PR, Baschal EE, Fain PR, Nanduri P, Triolo TM, Siebert JC, Armstrong TK, Babu SR, Rewers MJ, Gottlieb PA, Barker JM, Eisenbarth GS. Baker PR, et al. Among authors: fain pr. J Clin Endocrinol Metab. 2011 Jul;96(7):2154-62. doi: 10.1210/jc.2010-2964. Epub 2011 May 11. J Clin Endocrinol Metab. 2011. PMID: 21565792 Free PMC article.
Genetics of type 1A (immune mediated) diabetes.
Melanitou E, Fain P, Eisenbarth GS. Melanitou E, et al. J Autoimmun. 2003 Sep;21(2):93-8. doi: 10.1016/s0896-8411(03)00097-0. J Autoimmun. 2003. PMID: 12935776 Review.
A susceptibility locus on chromosome 6q greatly increases lung cancer risk among light and never smokers.
Amos CI, Pinney SM, Li Y, Kupert E, Lee J, de Andrade MA, Yang P, Schwartz AG, Fain PR, Gazdar A, Minna J, Wiest JS, Zeng D, Rothschild H, Mandal D, You M, Coons T, Gaba C, Bailey-Wilson JE, Anderson MW. Amos CI, et al. Among authors: fain pr. Cancer Res. 2010 Mar 15;70(6):2359-67. doi: 10.1158/0008-5472.CAN-09-3096. Epub 2010 Mar 9. Cancer Res. 2010. PMID: 20215501 Free PMC article.
A major lung cancer susceptibility locus maps to chromosome 6q23-25.
Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Wiest JS, Fain P, Schwartz AG, You M, Franklin W, Klein C, Gazdar A, Rothschild H, Mandal D, Coons T, Slusser J, Lee J, Gaba C, Kupert E, Perez A, Zhou X, Zeng D, Liu Q, Zhang Q, Seminara D, Minna J, Anderson MW. Bailey-Wilson JE, et al. Am J Hum Genet. 2004 Sep;75(3):460-74. doi: 10.1086/423857. Epub 2004 Jul 21. Am J Hum Genet. 2004. PMID: 15272417 Free PMC article.
Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
Wang JC, Cruchaga C, Saccone NL, Bertelsen S, Liu P, Budde JP, Duan W, Fox L, Grucza RA, Kern J, Mayo K, Reyes O, Rice J, Saccone SF, Spiegel N, Steinbach JH, Stitzel JA, Anderson MW, You M, Stevens VL, Bierut LJ, Goate AM; COGEND collaborators and GELCC collaborators. Wang JC, et al. Hum Mol Genet. 2009 Aug 15;18(16):3125-35. doi: 10.1093/hmg/ddp231. Epub 2009 May 14. Hum Mol Genet. 2009. PMID: 19443489 Free PMC article.
128 results