Dent P - Search Results

1

Vorinostat and sorafenib increase CD95 activation in gastrointestinal tumor cells through a Ca(2+)-de novo ceramide-PP2A-reactive oxygen species-dependent signaling pathway.

Park MA, Mitchell C, Zhang G, Yacoub A, Allegood J, Häussinger D, Reinehr R, Larner A, Spiegel S, Fisher PB, Voelkel-Johnson C, Ogretmen B, Grant S, Dent P. Park MA, et al. Among authors: dent p. Cancer Res. 2010 Aug 1;70(15):6313-24. doi: 10.1158/0008-5472.CAN-10-0999. Epub 2010 Jul 14. Cancer Res. 2010. PMID: 20631069 Free PMC article.

2

Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species.

Rahmani M, Reese E, Dai Y, Bauer C, Payne SG, Dent P, Spiegel S, Grant S. Rahmani M, et al. Among authors: dent p. Cancer Res. 2005 Mar 15;65(6):2422-32. doi: 10.1158/0008-5472.CAN-04-2440. Cancer Res. 2005. PMID: 15781658

3

MEK1/2 inhibition promotes Taxotere lethality in mammary tumors in vivo.

Yacoub A, Gilfor D, Hawkins W, Park MA, Hanna D, Hagan MP, Curiel DT, Fisher PB, Grant S, Dent P. Yacoub A, et al. Among authors: dent p. Cancer Biol Ther. 2006 Oct;5(10):1332-9. doi: 10.4161/cbt.5.10.3215. Epub 2006 Oct 15. Cancer Biol Ther. 2006. PMID: 16957420 Free article.

4

17-Allylamino-17-demethoxygeldanamycin enhances the lethality of deoxycholic acid in primary rodent hepatocytes and established cell lines.

Mitchell C, Park MA, Zhang G, Han SI, Harada H, Franklin RA, Yacoub A, Li PL, Hylemon PB, Grant S, Dent P. Mitchell C, et al. Among authors: dent p. Mol Cancer Ther. 2007 Feb;6(2):618-32. doi: 10.1158/1535-7163.MCT-06-0532. Mol Cancer Ther. 2007. PMID: 17308059

5

Radiation-induced cell signaling: inside-out and outside-in.

Valerie K, Yacoub A, Hagan MP, Curiel DT, Fisher PB, Grant S, Dent P. Valerie K, et al. Among authors: dent p. Mol Cancer Ther. 2007 Mar;6(3):789-801. doi: 10.1158/1535-7163.MCT-06-0596. Mol Cancer Ther. 2007. PMID: 17363476 Review.

6

Synergistic interactions between vorinostat and sorafenib in chronic myelogenous leukemia cells involve Mcl-1 and p21CIP1 down-regulation.

Dasmahapatra G, Yerram N, Dai Y, Dent P, Grant S. Dasmahapatra G, et al. Among authors: dent p. Clin Cancer Res. 2007 Jul 15;13(14):4280-90. doi: 10.1158/1078-0432.CCR-07-0835. Clin Cancer Res. 2007. Retraction in: Clin Cancer Res. 2016 Oct 1;22(19):4959. doi: 10.1158/1078-0432.CCR-16-1914. PMID: 17634558 Retracted.

7

Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells.

Mitchell C, Park MA, Zhang G, Yacoub A, Curiel DT, Fisher PB, Roberts JD, Grant S, Dent P. Mitchell C, et al. Among authors: dent p. Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3101-12. doi: 10.1158/1535-7163.MCT-07-0561. Epub 2007 Dec 7. Mol Cancer Ther. 2007. PMID: 18065490

8

Human chorionic gonadotropin (hCG) interacts with lovastatin and ionizing radiation to modulate prostate cancer cell viability in vivo.

Hamed H, Mitchell C, Park MA, Hanna D, Martin AP, Harrison B, Hawkins W, Curiel DA, Fisher PB, Grant S, Yacoub A, Hagan MP, Dent P. Hamed H, et al. Among authors: dent p. Cancer Biol Ther. 2008 Apr;7(4):587-93. doi: 10.4161/cbt.7.4.5543. Epub 2008 Jan 8. Cancer Biol Ther. 2008. PMID: 18379195 Free article.

9

Regulation of autophagy by ceramide-CD95-PERK signaling.

Park MA, Zhang G, Norris J, Hylemon PB, Fisher PB, Grant S, Dent P. Park MA, et al. Among authors: dent p. Autophagy. 2008 Oct;4(7):929-31. doi: 10.4161/auto.6732. Epub 2008 Oct 5. Autophagy. 2008. PMID: 18719356 Free PMC article.

10

Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation.

Zhang G, Park MA, Mitchell C, Hamed H, Rahmani M, Martin AP, Curiel DT, Yacoub A, Graf M, Lee R, Roberts JD, Fisher PB, Grant S, Dent P. Zhang G, et al. Among authors: dent p. Clin Cancer Res. 2008 Sep 1;14(17):5385-99. doi: 10.1158/1078-0432.CCR-08-0469. Clin Cancer Res. 2008. PMID: 18765530 Free PMC article.

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