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The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells.
Sharmeen S, Skrtic M, Sukhai MA, Hurren R, Gronda M, Wang X, Fonseca SB, Sun H, Wood TE, Ward R, Minden MD, Batey RA, Datti A, Wrana J, Kelley SO, Schimmer AD. Sharmeen S, et al. Among authors: batey ra. Blood. 2010 Nov 4;116(18):3593-603. doi: 10.1182/blood-2010-01-262675. Epub 2010 Jul 19. Blood. 2010. PMID: 20644115 Free article.
Targeting XIAP for the treatment of malignancy.
Schimmer AD, Dalili S, Batey RA, Riedl SJ. Schimmer AD, et al. Among authors: batey ra. Cell Death Differ. 2006 Feb;13(2):179-88. doi: 10.1038/sj.cdd.4401826. Cell Death Differ. 2006. PMID: 16322751 Review.
A novel inhibitor of glucose uptake sensitizes cells to FAS-induced cell death.
Wood TE, Dalili S, Simpson CD, Hurren R, Mao X, Saiz FS, Gronda M, Eberhard Y, Minden MD, Bilan PJ, Klip A, Batey RA, Schimmer AD. Wood TE, et al. Among authors: batey ra. Mol Cancer Ther. 2008 Nov;7(11):3546-55. doi: 10.1158/1535-7163.MCT-08-0569. Mol Cancer Ther. 2008. PMID: 19001437
The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma.
Xu GW, Ali M, Wood TE, Wong D, Maclean N, Wang X, Gronda M, Skrtic M, Li X, Hurren R, Mao X, Venkatesan M, Beheshti Zavareh R, Ketela T, Reed JC, Rose D, Moffat J, Batey RA, Dhe-Paganon S, Schimmer AD. Xu GW, et al. Among authors: batey ra. Blood. 2010 Mar 18;115(11):2251-9. doi: 10.1182/blood-2009-07-231191. Epub 2010 Jan 14. Blood. 2010. PMID: 20075161 Free PMC article.
Effect of noncompetitive proteasome inhibition on bortezomib resistance.
Li X, Wood TE, Sprangers R, Jansen G, Franke NE, Mao X, Wang X, Zhang Y, Verbrugge SE, Adomat H, Li ZH, Trudel S, Chen C, Religa TL, Jamal N, Messner H, Cloos J, Rose DR, Navon A, Guns E, Batey RA, Kay LE, Schimmer AD. Li X, et al. Among authors: batey ra. J Natl Cancer Inst. 2010 Jul 21;102(14):1069-82. doi: 10.1093/jnci/djq198. Epub 2010 May 26. J Natl Cancer Inst. 2010. PMID: 20505154
A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway.
Mao X, Cao B, Wood TE, Hurren R, Tong J, Wang X, Wang W, Li J, Jin Y, Sun W, Spagnuolo PA, MacLean N, Moran MF, Datti A, Wrana J, Batey RA, Schimmer AD. Mao X, et al. Among authors: batey ra. Blood. 2011 Feb 10;117(6):1986-97. doi: 10.1182/blood-2010-05-284810. Epub 2010 Dec 6. Blood. 2011. PMID: 21135258 Free article.
83 results