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The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells.
Sharmeen S, Skrtic M, Sukhai MA, Hurren R, Gronda M, Wang X, Fonseca SB, Sun H, Wood TE, Ward R, Minden MD, Batey RA, Datti A, Wrana J, Kelley SO, Schimmer AD. Sharmeen S, et al. Among authors: fonseca sb. Blood. 2010 Nov 4;116(18):3593-603. doi: 10.1182/blood-2010-01-262675. Epub 2010 Jul 19. Blood. 2010. PMID: 20644115 Free article.
Mitochondria-penetrating peptides.
Horton KL, Stewart KM, Fonseca SB, Guo Q, Kelley SO. Horton KL, et al. Among authors: fonseca sb. Chem Biol. 2008 Apr;15(4):375-82. doi: 10.1016/j.chembiol.2008.03.015. Chem Biol. 2008. PMID: 18420144
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