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Control systems and decision making for antibody production.
Goodnow CC, Vinuesa CG, Randall KL, Mackay F, Brink R. Goodnow CC, et al. Among authors: mackay f. Nat Immunol. 2010 Aug;11(8):681-8. doi: 10.1038/ni.1900. Epub 2010 Jul 20. Nat Immunol. 2010. PMID: 20644574 Review.
Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.
Randall KL, Lambe T, Johnson AL, Treanor B, Kucharska E, Domaschenz H, Whittle B, Tze LE, Enders A, Crockford TL, Bouriez-Jones T, Alston D, Cyster JG, Lenardo MJ, Mackay F, Deenick EK, Tangye SG, Chan TD, Camidge T, Brink R, Vinuesa CG, Batista FD, Cornall RJ, Goodnow CC. Randall KL, et al. Among authors: mackay f. Nat Immunol. 2009 Dec;10(12):1283-91. doi: 10.1038/ni.1820. Epub 2009 Nov 8. Nat Immunol. 2009. PMID: 19898472 Free PMC article.
B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPL2A.
Bergmann H, Yabas M, Short A, Miosge L, Barthel N, Teh CE, Roots CM, Bull KR, Jeelall Y, Horikawa K, Whittle B, Balakishnan B, Sjollema G, Bertram EM, Mackay F, Rimmer AJ, Cornall RJ, Field MA, Andrews TD, Goodnow CC, Enders A. Bergmann H, et al. Among authors: mackay f. J Exp Med. 2013 Jan 14;210(1):31-40. doi: 10.1084/jem.20121076. Epub 2012 Dec 24. J Exp Med. 2013. PMID: 23267016 Free PMC article.
Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.
He J, Tsai LM, Leong YA, Hu X, Ma CS, Chevalier N, Sun X, Vandenberg K, Rockman S, Ding Y, Zhu L, Wei W, Wang C, Karnowski A, Belz GT, Ghali JR, Cook MC, Riminton DS, Veillette A, Schwartzberg PL, Mackay F, Brink R, Tangye SG, Vinuesa CG, Mackay CR, Li Z, Yu D. He J, et al. Among authors: mackay f, mackay cr. Immunity. 2013 Oct 17;39(4):770-81. doi: 10.1016/j.immuni.2013.09.007. Immunity. 2013. PMID: 24138884 Free article.
Cracking the BAFF code.
Mackay F, Schneider P. Mackay F, et al. Nat Rev Immunol. 2009 Jul;9(7):491-502. doi: 10.1038/nri2572. Nat Rev Immunol. 2009. PMID: 19521398 Free article. Review.
216 results