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Abnormal Tau phosphorylation of the Alzheimer-type also occurs during mitosis.
Delobel P, Flament S, Hamdane M, Mailliot C, Sambo AV, Bégard S, Sergeant N, Delacourte A, Vilain JP, Buée L. Delobel P, et al. Among authors: sergeant n. J Neurochem. 2002 Oct;83(2):412-20. doi: 10.1046/j.1471-4159.2002.01143.x. J Neurochem. 2002. PMID: 12423251 Free article.
Pin1: a therapeutic target in Alzheimer neurodegeneration.
Hamdane M, Smet C, Sambo AV, Leroy A, Wieruszeski JM, Delobel P, Maurage CA, Ghestem A, Wintjens R, Bégard S, Sergeant N, Delacourte A, Horvath D, Landrieu I, Lippens G, Buée L. Hamdane M, et al. Among authors: sergeant n. J Mol Neurosci. 2002 Dec;19(3):275-87. doi: 10.1385/JMN:19:3:275. J Mol Neurosci. 2002. PMID: 12540053
In vitro models of age-related neurodegenerative disorders.
Delacourte A, Sergeant N, Buée L. Delacourte A, et al. Among authors: sergeant n. Exp Gerontol. 2003 Nov-Dec;38(11-12):1309-17. doi: 10.1016/j.exger.2003.09.010. Exp Gerontol. 2003. PMID: 14698810 Review.
Tau protein as a differential biomarker of tauopathies.
Sergeant N, Delacourte A, Buée L. Sergeant N, et al. Biochim Biophys Acta. 2005 Jan 3;1739(2-3):179-97. doi: 10.1016/j.bbadis.2004.06.020. Biochim Biophys Acta. 2005. PMID: 15615637 Free article. Review.
Pin1 allows for differential Tau dephosphorylation in neuronal cells.
Hamdane M, Dourlen P, Bretteville A, Sambo AV, Ferreira S, Ando K, Kerdraon O, Bégard S, Geay L, Lippens G, Sergeant N, Delacourte A, Maurage CA, Galas MC, Buée L. Hamdane M, et al. Among authors: sergeant n. Mol Cell Neurosci. 2006 May-Jun;32(1-2):155-60. doi: 10.1016/j.mcn.2006.03.006. Epub 2006 May 11. Mol Cell Neurosci. 2006. PMID: 16697218
Alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies.
Vingtdeux V, Hamdane M, Loyens A, Gelé P, Drobeck H, Bégard S, Galas MC, Delacourte A, Beauvillain JC, Buée L, Sergeant N. Vingtdeux V, et al. Among authors: sergeant n. J Biol Chem. 2007 Jun 22;282(25):18197-18205. doi: 10.1074/jbc.M609475200. Epub 2007 Apr 27. J Biol Chem. 2007. PMID: 17468104 Free article.
We showed recently that the amyloid intracellular domain (AICD), which is released by gamma-secretase cleavage of APP C-terminal fragments (CTFs), is strongly increased in cells treated with alkalizing drugs (Vingtdeux, V., Hamdane, M., Begard, S., Loyens, A., Delacourte, A., Bea …
We showed recently that the amyloid intracellular domain (AICD), which is released by gamma-secretase cleavage of APP C-terminal fragments ( …
138 results