Johnson KR - Search Results

1

The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice.

Shin JB, Longo-Guess CM, Gagnon LH, Saylor KW, Dumont RA, Spinelli KJ, Pagana JM, Wilmarth PA, David LL, Gillespie PG, Johnson KR. Shin JB, et al. Among authors: johnson kr. J Neurosci. 2010 Jul 21;30(29):9683-94. doi: 10.1523/JNEUROSCI.1541-10.2010. J Neurosci. 2010. PMID: 20660251 Free PMC article.

2

The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function.

Gagnon LH, Longo-Guess CM, Berryman M, Shin JB, Saylor KW, Yu H, Gillespie PG, Johnson KR. Gagnon LH, et al. Among authors: johnson kr. J Neurosci. 2006 Oct 4;26(40):10188-98. doi: 10.1523/JNEUROSCI.2166-06.2006. J Neurosci. 2006. PMID: 17021174 Free PMC article.

3

A QTL on Chr 5 modifies hearing loss associated with the fascin-2 variant of DBA/2J mice.

Johnson KR, Longo-Guess CM, Gagnon LH. Johnson KR, et al. Mamm Genome. 2015 Aug;26(7-8):338-47. doi: 10.1007/s00335-015-9574-y. Epub 2015 Jun 20. Mamm Genome. 2015. PMID: 26092689 Free PMC article.

4

ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical Structures in Developing Vestibular Hair Cells.

Krey JF, Dumont RA, Wilmarth PA, David LL, Johnson KR, Barr-Gillespie PG. Krey JF, et al. Among authors: johnson kr. J Neurosci. 2018 Jan 24;38(4):843-857. doi: 10.1523/JNEUROSCI.2658-17.2017. Epub 2017 Dec 8. J Neurosci. 2018. PMID: 29222402 Free PMC article.

5

A locus on distal chromosome 11 (ahl8) and its interaction with Cdh23 ahl underlie the early onset, age-related hearing loss of DBA/2J mice.

Johnson KR, Longo-Guess C, Gagnon LH, Yu H, Zheng QY. Johnson KR, et al. Genomics. 2008 Oct;92(4):219-25. doi: 10.1016/j.ygeno.2008.06.007. Epub 2008 Aug 15. Genomics. 2008. PMID: 18662770 Free PMC article.

6

Association of a citrate synthase missense mutation with age-related hearing loss in A/J mice.

Johnson KR, Gagnon LH, Longo-Guess C, Kane KL. Johnson KR, et al. Neurobiol Aging. 2012 Aug;33(8):1720-9. doi: 10.1016/j.neurobiolaging.2011.05.009. Epub 2011 Jul 30. Neurobiol Aging. 2012. PMID: 21803452 Free PMC article.

7

Genetic background effects on age-related hearing loss associated with Cdh23 variants in mice.

Kane KL, Longo-Guess CM, Gagnon LH, Ding D, Salvi RJ, Johnson KR. Kane KL, et al. Among authors: johnson kr. Hear Res. 2012 Jan;283(1-2):80-8. doi: 10.1016/j.heares.2011.11.007. Epub 2011 Nov 22. Hear Res. 2012. PMID: 22138310 Free PMC article.

8

Mutations of the mouse ELMO domain containing 1 gene (Elmod1) link small GTPase signaling to actin cytoskeleton dynamics in hair cell stereocilia.

Johnson KR, Longo-Guess CM, Gagnon LH. Johnson KR, et al. PLoS One. 2012;7(4):e36074. doi: 10.1371/journal.pone.0036074. Epub 2012 Apr 27. PLoS One. 2012. PMID: 22558334 Free PMC article.

9

Effects of Cdh23 single nucleotide substitutions on age-related hearing loss in C57BL/6 and 129S1/Sv mice and comparisons with congenic strains.

Johnson KR, Tian C, Gagnon LH, Jiang H, Ding D, Salvi R. Johnson KR, et al. Sci Rep. 2017 Mar 13;7:44450. doi: 10.1038/srep44450. Sci Rep. 2017. PMID: 28287619 Free PMC article.

10

Targeted knockout and lacZ reporter expression of the mouse Tmhs deafness gene and characterization of the hscy-2J mutation.

Longo-Guess CM, Gagnon LH, Fritzsch B, Johnson KR. Longo-Guess CM, et al. Among authors: johnson kr. Mamm Genome. 2007 Sep;18(9):646-56. doi: 10.1007/s00335-007-9049-x. Epub 2007 Sep 18. Mamm Genome. 2007. PMID: 17876667 Free PMC article.

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