Siderovski DP - Search Results

1

A homogeneous method to measure nucleotide exchange by α-subunits of heterotrimeric G-proteins using fluorescence polarization.

Muller RE, Klein KR, Hutsell SQ, Siderovski DP, Kimple AJ. Muller RE, et al. Among authors: siderovski dp. Assay Drug Dev Technol. 2010 Oct;8(5):621-4. doi: 10.1089/adt.2010.0286. Epub 2010 Jul 27. Assay Drug Dev Technol. 2010. PMID: 20662737 Free PMC article.

2

RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity.

Kimple RJ, De Vries L, Tronchère H, Behe CI, Morris RA, Gist Farquhar M, Siderovski DP. Kimple RJ, et al. Among authors: siderovski dp. J Biol Chem. 2001 Aug 3;276(31):29275-81. doi: 10.1074/jbc.M103208200. Epub 2001 May 31. J Biol Chem. 2001. PMID: 11387333 Free article.

3

Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits.

Kimple RJ, Kimple ME, Betts L, Sondek J, Siderovski DP. Kimple RJ, et al. Among authors: siderovski dp. Nature. 2002 Apr 25;416(6883):878-81. doi: 10.1038/416878a. Nature. 2002. PMID: 11976690

4

Established and emerging fluorescence-based assays for G-protein function: heterotrimeric G-protein alpha subunits and regulator of G-protein signaling (RGS) proteins.

Kimple RJ, Jones MB, Shutes A, Yerxa BR, Siderovski DP, Willard FS. Kimple RJ, et al. Among authors: siderovski dp. Comb Chem High Throughput Screen. 2003 Jun;6(4):399-407. doi: 10.2174/138620703106298491. Comb Chem High Throughput Screen. 2003. PMID: 12769684

5

Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif.

Kimple RJ, Willard FS, Hains MD, Jones MB, Nweke GK, Siderovski DP. Kimple RJ, et al. Among authors: siderovski dp. Biochem J. 2004 Mar 15;378(Pt 3):801-8. doi: 10.1042/BJ20031686. Biochem J. 2004. PMID: 14656218 Free PMC article.

6

Fluorescence-based assays for RGS box function.

Willard FS, Kimple RJ, Kimple AJ, Johnston CA, Siderovski DP. Willard FS, et al. Among authors: siderovski dp. Methods Enzymol. 2004;389:56-71. doi: 10.1016/S0076-6879(04)89004-9. Methods Enzymol. 2004. PMID: 15313559 Review.

7

Purification and in vitro functional analyses of RGS12 and RGS14 GoLoco motif peptides.

Kimple RJ, Willard FS, Siderovski DP. Kimple RJ, et al. Among authors: siderovski dp. Methods Enzymol. 2004;390:416-36. doi: 10.1016/S0076-6879(04)90026-2. Methods Enzymol. 2004. PMID: 15488192

8

Structural and evolutionary division of phosphotyrosine binding (PTB) domains.

Uhlik MT, Temple B, Bencharit S, Kimple AJ, Siderovski DP, Johnson GL. Uhlik MT, et al. Among authors: siderovski dp. J Mol Biol. 2005 Jan 7;345(1):1-20. doi: 10.1016/j.jmb.2004.10.038. J Mol Biol. 2005. PMID: 15567406 Review.

9

A direct fluorescence-based assay for RGS domain GTPase accelerating activity.

Willard FS, Kimple AJ, Johnston CA, Siderovski DP. Willard FS, et al. Among authors: siderovski dp. Anal Biochem. 2005 May 15;340(2):341-51. doi: 10.1016/j.ab.2005.02.015. Anal Biochem. 2005. PMID: 15840508

10

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits.

Siderovski DP, Willard FS. Siderovski DP, et al. Int J Biol Sci. 2005;1(2):51-66. doi: 10.7150/ijbs.1.51. Epub 2005 Apr 1. Int J Biol Sci. 2005. PMID: 15951850 Free PMC article. Review.

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