Casellas R - Search Results

1

PTIP promotes chromatin changes critical for immunoglobulin class switch recombination.

Daniel JA, Santos MA, Wang Z, Zang C, Schwab KR, Jankovic M, Filsuf D, Chen HT, Gazumyan A, Yamane A, Cho YW, Sun HW, Ge K, Peng W, Nussenzweig MC, Casellas R, Dressler GR, Zhao K, Nussenzweig A. Daniel JA, et al. Among authors: casellas r. Science. 2010 Aug 20;329(5994):917-23. doi: 10.1126/science.1187942. Epub 2010 Jul 29. Science. 2010. PMID: 20671152 Free PMC article.

2

RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycle.

Yamane A, Robbiani DF, Resch W, Bothmer A, Nakahashi H, Oliveira T, Rommel PC, Brown EJ, Nussenzweig A, Nussenzweig MC, Casellas R. Yamane A, et al. Among authors: casellas r. Cell Rep. 2013 Jan 31;3(1):138-47. doi: 10.1016/j.celrep.2012.12.006. Epub 2013 Jan 3. Cell Rep. 2013. PMID: 23291097 Free PMC article.

3

Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.

Di Virgilio M, Callen E, Yamane A, Zhang W, Jankovic M, Gitlin AD, Feldhahn N, Resch W, Oliveira TY, Chait BT, Nussenzweig A, Casellas R, Robbiani DF, Nussenzweig MC. Di Virgilio M, et al. Among authors: casellas r. Science. 2013 Feb 8;339(6120):711-5. doi: 10.1126/science.1230624. Epub 2013 Jan 10. Science. 2013. PMID: 23306439 Free PMC article.

4

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching.

Petersen S, Casellas R, Reina-San-Martin B, Chen HT, Difilippantonio MJ, Wilson PC, Hanitsch L, Celeste A, Muramatsuk M, Pilch DR, Redon C, Ried T, Bonner WM, Honjo T, Nussenzweig MC, Nussenzweig A. Petersen S, et al. Among authors: casellas r. Nature. 2001 Dec 6;414(6864):660-665. doi: 10.1038/414660a. Nature. 2001. PMID: 11740565 Free PMC article.

5

Restricting activation-induced cytidine deaminase tumorigenic activity in B lymphocytes.

Casellas R, Yamane A, Kovalchuk AL, Potter M. Casellas R, et al. Immunology. 2009 Mar;126(3):316-28. doi: 10.1111/j.1365-2567.2008.03050.x. Immunology. 2009. PMID: 19302140 Free PMC article. Review.

6

Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5.

Pavri R, Gazumyan A, Jankovic M, Di Virgilio M, Klein I, Ansarah-Sobrinho C, Resch W, Yamane A, Reina San-Martin B, Barreto V, Nieland TJ, Root DE, Casellas R, Nussenzweig MC. Pavri R, et al. Among authors: casellas r. Cell. 2010 Oct 1;143(1):122-33. doi: 10.1016/j.cell.2010.09.017. Cell. 2010. PMID: 20887897 Free PMC article.

7

Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes.

Yamane A, Resch W, Kuo N, Kuchen S, Li Z, Sun HW, Robbiani DF, McBride K, Nussenzweig MC, Casellas R. Yamane A, et al. Among authors: casellas r. Nat Immunol. 2011 Jan;12(1):62-9. doi: 10.1038/ni.1964. Epub 2010 Nov 28. Nat Immunol. 2011. PMID: 21113164 Free PMC article.

8

Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.

Klein IA, Resch W, Jankovic M, Oliveira T, Yamane A, Nakahashi H, Di Virgilio M, Bothmer A, Nussenzweig A, Robbiani DF, Casellas R, Nussenzweig MC. Klein IA, et al. Among authors: casellas r. Cell. 2011 Sep 30;147(1):95-106. doi: 10.1016/j.cell.2011.07.048. Cell. 2011. PMID: 21962510 Free PMC article.

9

Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching.

Bothmer A, Rommel PC, Gazumyan A, Polato F, Reczek CR, Muellenbeck MF, Schaetzlein S, Edelmann W, Chen PL, Brosh RM Jr, Casellas R, Ludwig T, Baer R, Nussenzweig A, Nussenzweig MC, Robbiani DF. Bothmer A, et al. Among authors: casellas r. J Exp Med. 2013 Jan 14;210(1):115-23. doi: 10.1084/jem.20121975. Epub 2012 Dec 17. J Exp Med. 2013. PMID: 23254285 Free PMC article.

10

Epigenetic targeting of activation-induced cytidine deaminase.

Wang Q, Oliveira T, Jankovic M, Silva IT, Hakim O, Yao K, Gazumyan A, Mayer CT, Pavri R, Casellas R, Nussenzweig MC, Robbiani DF. Wang Q, et al. Among authors: casellas r. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18667-72. doi: 10.1073/pnas.1420575111. Epub 2014 Dec 15. Proc Natl Acad Sci U S A. 2014. PMID: 25512519 Free PMC article.

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