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The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells.
Renner B, Coleman K, Goldberg R, Amura C, Holland-Neidermyer A, Pierce K, Orth HN, Molina H, Ferreira VP, Cortes C, Pangburn MK, Holers VM, Thurman JM. Renner B, et al. Among authors: ferreira vp. J Immunol. 2010 Sep 1;185(5):3086-94. doi: 10.4049/jimmunol.1000111. Epub 2010 Jul 30. J Immunol. 2010. PMID: 20675597 Free PMC article.
Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism.
Herbert AP, Deakin JA, Schmidt CQ, Blaum BS, Egan C, Ferreira VP, Pangburn MK, Lyon M, Uhrín D, Barlow PN. Herbert AP, et al. Among authors: ferreira vp. J Biol Chem. 2007 Jun 29;282(26):18960-8. doi: 10.1074/jbc.M609636200. Epub 2007 Mar 13. J Biol Chem. 2007. PMID: 17360715 Free article.
Polyanion-induced self-association of complement factor H.
Pangburn MK, Rawal N, Cortes C, Alam MN, Ferreira VP, Atkinson MA. Pangburn MK, et al. Among authors: ferreira vp. J Immunol. 2009 Jan 15;182(2):1061-8. doi: 10.4049/jimmunol.182.2.1061. J Immunol. 2009. PMID: 19124749 Free PMC article.
70 results