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Global gene expression profiling reveals widespread yet distinctive translational responses to different eukaryotic translation initiation factor 2B-targeting stress pathways.
Smirnova JB, Selley JN, Sanchez-Cabo F, Carroll K, Eddy AA, McCarthy JE, Hubbard SJ, Pavitt GD, Grant CM, Ashe MP. Smirnova JB, et al. Among authors: pavitt gd. Mol Cell Biol. 2005 Nov;25(21):9340-9. doi: 10.1128/MCB.25.21.9340-9349.2005. Mol Cell Biol. 2005. PMID: 16227585 Free PMC article.
Translation controlled.
Pavitt GD, Ashe MP. Pavitt GD, et al. Genome Biol. 2008 Oct 21;9(10):323. doi: 10.1186/gb-2008-9-10-323. Genome Biol. 2008. PMID: 18983689 Free PMC article.
Fusel alcohols regulate translation initiation by inhibiting eIF2B to reduce ternary complex in a mechanism that may involve altering the integrity and dynamics of the eIF2B body.
Taylor EJ, Campbell SG, Griffiths CD, Reid PJ, Slaven JW, Harrison RJ, Sims PF, Pavitt GD, Delneri D, Ashe MP. Taylor EJ, et al. Among authors: pavitt gd. Mol Biol Cell. 2010 Jul 1;21(13):2202-16. doi: 10.1091/mbc.e09-11-0962. Epub 2010 May 5. Mol Biol Cell. 2010. PMID: 20444979 Free PMC article.
Mechanisms of translational regulation by a human eIF5-mimic protein.
Singh CR, Watanabe R, Zhou D, Jennings MD, Fukao A, Lee B, Ikeda Y, Chiorini JA, Campbell SG, Ashe MP, Fujiwara T, Wek RC, Pavitt GD, Asano K. Singh CR, et al. Among authors: pavitt gd. Nucleic Acids Res. 2011 Oct;39(19):8314-28. doi: 10.1093/nar/gkr339. Epub 2011 Jul 10. Nucleic Acids Res. 2011. PMID: 21745818 Free PMC article.
Puf3p induces translational repression of genes linked to oxidative stress.
Rowe W, Kershaw CJ, Castelli LM, Costello JL, Ashe MP, Grant CM, Sims PF, Pavitt GD, Hubbard SJ. Rowe W, et al. Among authors: pavitt gd. Nucleic Acids Res. 2014 Jan;42(2):1026-41. doi: 10.1093/nar/gkt948. Epub 2013 Oct 25. Nucleic Acids Res. 2014. PMID: 24163252 Free PMC article.
Global mRNA selection mechanisms for translation initiation.
Costello J, Castelli LM, Rowe W, Kershaw CJ, Talavera D, Mohammad-Qureshi SS, Sims PF, Grant CM, Pavitt GD, Hubbard SJ, Ashe MP. Costello J, et al. Among authors: pavitt gd. Genome Biol. 2015 Jan 5;16(1):10. doi: 10.1186/s13059-014-0559-z. Genome Biol. 2015. PMID: 25650959 Free PMC article.
70 results