Blagg BS - Search Results

1

Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice.

Urban MJ, Li C, Yu C, Lu Y, Krise JM, McIntosh MP, Rajewski RA, Blagg BS, Dobrowsky RT. Urban MJ, et al. Among authors: blagg bs. ASN Neuro. 2010 Aug 11;2(4):e00040. doi: 10.1042/AN20100015. ASN Neuro. 2010. PMID: 20711301 Free PMC article.

2

Hsp90 inhibitors identified from a library of novobiocin analogues.

Yu XM, Shen G, Neckers L, Blake H, Holzbeierlein J, Cronk B, Blagg BS. Yu XM, et al. Among authors: blagg bs. J Am Chem Soc. 2005 Sep 21;127(37):12778-9. doi: 10.1021/ja0535864. J Am Chem Soc. 2005. PMID: 16159253

3

A library of noviosylated coumarin analogues.

Huang YT, Blagg BS. Huang YT, et al. Among authors: blagg bs. J Org Chem. 2007 May 11;72(10):3609-13. doi: 10.1021/jo062083t. Epub 2007 Mar 1. J Org Chem. 2007. PMID: 17328573

4

Development of novobiocin analogues that manifest anti-proliferative activity against several cancer cell lines.

Burlison JA, Avila C, Vielhauer G, Lubbers DJ, Holzbeierlein J, Blagg BS. Burlison JA, et al. Among authors: blagg bs. J Org Chem. 2008 Mar 21;73(6):2130-7. doi: 10.1021/jo702191a. Epub 2008 Feb 23. J Org Chem. 2008. PMID: 18293999

5

Gedunin, a novel hsp90 inhibitor: semisynthesis of derivatives and preliminary structure-activity relationships.

Brandt GE, Schmidt MD, Prisinzano TE, Blagg BS. Brandt GE, et al. Among authors: blagg bs. J Med Chem. 2008 Oct 23;51(20):6495-502. doi: 10.1021/jm8007486. Epub 2008 Sep 25. J Med Chem. 2008. PMID: 18816111 Free PMC article.

6

Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket.

Donnelly A, Blagg BS. Donnelly A, et al. Among authors: blagg bs. Curr Med Chem. 2008;15(26):2702-17. doi: 10.2174/092986708786242895. Curr Med Chem. 2008. PMID: 18991631 Free PMC article. Review.

7

Neuroprotective activity and evaluation of Hsp90 inhibitors in an immortalized neuronal cell line.

Lu Y, Ansar S, Michaelis ML, Blagg BS. Lu Y, et al. Among authors: blagg bs. Bioorg Med Chem. 2009 Feb 15;17(4):1709-15. doi: 10.1016/j.bmc.2008.12.047. Epub 2008 Dec 25. Bioorg Med Chem. 2009. PMID: 19138859 Free PMC article.

8

Natural product inhibitors of Hsp90: potential leads for drug discovery.

Amolins MW, Blagg BS. Amolins MW, et al. Among authors: blagg bs. Mini Rev Med Chem. 2009 Feb;9(2):140-52. doi: 10.2174/138955709787316056. Mini Rev Med Chem. 2009. PMID: 19200020 Free PMC article. Review.

9

Characterization of a novel novobiocin analogue as a putative C-terminal inhibitor of heat shock protein 90 in prostate cancer cells.

Matthews SB, Vielhauer GA, Manthe CA, Chaguturu VK, Szabla K, Matts RL, Donnelly AC, Blagg BS, Holzbeierlein JM. Matthews SB, et al. Among authors: blagg bs. Prostate. 2010 Jan 1;70(1):27-36. doi: 10.1002/pros.21035. Prostate. 2010. PMID: 19739131 Free PMC article.

10

KU135, a novel novobiocin-derived C-terminal inhibitor of the 90-kDa heat shock protein, exerts potent antiproliferative effects in human leukemic cells.

Shelton SN, Shawgo ME, Matthews SB, Lu Y, Donnelly AC, Szabla K, Tanol M, Vielhauer GA, Rajewski RA, Matts RL, Blagg BS, Robertson JD. Shelton SN, et al. Among authors: blagg bs. Mol Pharmacol. 2009 Dec;76(6):1314-22. doi: 10.1124/mol.109.058545. Epub 2009 Sep 9. Mol Pharmacol. 2009. PMID: 19741006 Free PMC article.

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