Horton SJ - Search Results

1

BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34+ cells.

Rizo A, Horton SJ, Olthof S, Dontje B, Ausema A, van Os R, van den Boom V, Vellenga E, de Haan G, Schuringa JJ. Rizo A, et al. Among authors: horton sj. Blood. 2010 Nov 25;116(22):4621-30. doi: 10.1182/blood-2010-02-270660. Epub 2010 Aug 19. Blood. 2010. PMID: 20724541 Free article.

2

MLL-AF9-mediated immortalization of human hematopoietic cells along different lineages changes during ontogeny.

Horton SJ, Jaques J, Woolthuis C, van Dijk J, Mesuraca M, Huls G, Morrone G, Vellenga E, Schuringa JJ. Horton SJ, et al. Leukemia. 2013 Apr;27(5):1116-26. doi: 10.1038/leu.2012.343. Epub 2012 Nov 26. Leukemia. 2013. PMID: 23178754

3

Genetic and epigenetic alterations that drive leukemic stem cell self-renewal.

van den Boom V, Horton SJ, Schuringa JJ. van den Boom V, et al. Among authors: horton sj. J Stem Cells. 2012;7(3):155-79. J Stem Cells. 2012. PMID: 23619382 Review.

4

Genetically engineered mesenchymal stromal cells produce IL-3 and TPO to further improve human scaffold-based xenograft models.

Carretta M, de Boer B, Jaques J, Antonelli A, Horton SJ, Yuan H, de Bruijn JD, Groen RWJ, Vellenga E, Schuringa JJ. Carretta M, et al. Among authors: horton sj. Exp Hematol. 2017 Jul;51:36-46. doi: 10.1016/j.exphem.2017.04.008. Epub 2017 Apr 26. Exp Hematol. 2017. PMID: 28456746 Free article.

5

BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9+ leukemic cells.

Carretta M, Brouwers-Vos AZ, Bosman M, Horton SJ, Martens JHA, Vellenga E, Schuringa JJ. Carretta M, et al. Among authors: horton sj. PLoS One. 2017 Dec 14;12(12):e0189102. doi: 10.1371/journal.pone.0189102. eCollection 2017. PLoS One. 2017. PMID: 29240787 Free PMC article.

6

The AAA+ ATPase RUVBL2 is a critical mediator of MLL-AF9 oncogenesis.

Osaki H, Walf-Vorderwülbecke V, Mangolini M, Zhao L, Horton SJ, Morrone G, Schuringa JJ, de Boer J, Williams O. Osaki H, et al. Among authors: horton sj. Leukemia. 2013 Jul;27(7):1461-8. doi: 10.1038/leu.2013.42. Epub 2013 Feb 13. Leukemia. 2013. PMID: 23403462

7

Zinc finger protein 521 antagonizes early B-cell factor 1 and modulates the B-lymphoid differentiation of primary hematopoietic progenitors.

Mega T, Lupia M, Amodio N, Horton SJ, Mesuraca M, Pelaggi D, Agosti V, Grieco M, Chiarella E, Spina R, Moore MA, Schuringa JJ, Bond HM, Morrone G. Mega T, et al. Among authors: horton sj. Cell Cycle. 2011 Jul 1;10(13):2129-39. doi: 10.4161/cc.10.13.16045. Epub 2011 Jul 1. Cell Cycle. 2011. PMID: 21593590

8

Acute myeloid leukemia induced by MLL-ENL is cured by oncogene ablation despite acquisition of complex genetic abnormalities.

Horton SJ, Walf-Vorderwülbecke V, Chatters SJ, Sebire NJ, de Boer J, Williams O. Horton SJ, et al. Blood. 2009 May 14;113(20):4922-9. doi: 10.1182/blood-2008-07-170480. Epub 2008 Nov 24. Blood. 2009. PMID: 19029444 Free article.

9

Frat2 mediates the oncogenic activation of Rac by MLL fusions.

Walf-Vorderwülbecke V, de Boer J, Horton SJ, van Amerongen R, Proost N, Berns A, Williams O. Walf-Vorderwülbecke V, et al. Among authors: horton sj. Blood. 2012 Dec 6;120(24):4819-28. doi: 10.1182/blood-2012-05-432534. Epub 2012 Oct 16. Blood. 2012. PMID: 23074275 Free article.

10

TEL-AML1 promotes development of specific hematopoietic lineages consistent with preleukemic activity.

Morrow M, Horton S, Kioussis D, Brady HJ, Williams O. Morrow M, et al. Blood. 2004 May 15;103(10):3890-6. doi: 10.1182/blood-2003-10-3695. Epub 2004 Jan 15. Blood. 2004. PMID: 14726384 Free article.

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