Kerr ID - Search Results

1

Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1.

Crowley E, O'Mara ML, Kerr ID, Callaghan R. Crowley E, et al. Among authors: kerr id. FEBS J. 2010 Oct;277(19):3974-85. doi: 10.1111/j.1742-4658.2010.07789.x. Epub 2010 Aug 20. FEBS J. 2010. PMID: 20731718 Free article.

2

Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle.

Rosenberg MF, Velarde G, Ford RC, Martin C, Berridge G, Kerr ID, Callaghan R, Schmidlin A, Wooding C, Linton KJ, Higgins CF. Rosenberg MF, et al. Among authors: kerr id. EMBO J. 2001 Oct 15;20(20):5615-25. doi: 10.1093/emboj/20.20.5615. EMBO J. 2001. PMID: 11598005 Free PMC article.

3

The nucleotide-binding domains of P-glycoprotein. Functional symmetry in the isolated domain demonstrated by N-ethylmaleimide labelling.

Berridge G, Walker JA, Callaghan R, Kerr ID. Berridge G, et al. Among authors: kerr id. Eur J Biochem. 2003 Apr;270(7):1483-92. doi: 10.1046/j.1432-1033.2003.03514.x. Eur J Biochem. 2003. PMID: 12654004 Free article.

4

Communication between the nucleotide binding domains of P-glycoprotein occurs via conformational changes that involve residue 508.

Gabriel MP, Storm J, Rothnie A, Taylor AM, Linton KJ, Kerr ID, Callaghan R. Gabriel MP, et al. Among authors: kerr id. Biochemistry. 2003 Jul 1;42(25):7780-9. doi: 10.1021/bi0341049. Biochemistry. 2003. PMID: 12820887

5

Definition of the domain boundaries is critical to the expression of the nucleotide-binding domains of P-glycoprotein.

Kerr ID, Berridge G, Linton KJ, Higgins CF, Callaghan R. Kerr ID, et al. Eur Biophys J. 2003 Nov;32(7):644-54. doi: 10.1007/s00249-003-0327-6. Epub 2003 Jun 26. Eur Biophys J. 2003. PMID: 12830334

6

The topography of transmembrane segment six is altered during the catalytic cycle of P-glycoprotein.

Rothnie A, Storm J, Campbell J, Linton KJ, Kerr ID, Callaghan R. Rothnie A, et al. Among authors: kerr id. J Biol Chem. 2004 Aug 13;279(33):34913-21. doi: 10.1074/jbc.M405336200. Epub 2004 Jun 10. J Biol Chem. 2004. PMID: 15192095 Free article.

7

The coupling mechanism of P-glycoprotein involves residue L339 in the sixth membrane spanning segment.

Rothnie A, Storm J, McMahon R, Taylor A, Kerr ID, Callaghan R. Rothnie A, et al. Among authors: kerr id. FEBS Lett. 2005 Jul 18;579(18):3984-90. doi: 10.1016/j.febslet.2005.06.030. FEBS Lett. 2005. PMID: 16004994 Free article.

8

The translocation mechanism of P-glycoprotein.

Callaghan R, Ford RC, Kerr ID. Callaghan R, et al. Among authors: kerr id. FEBS Lett. 2006 Feb 13;580(4):1056-63. doi: 10.1016/j.febslet.2005.11.083. Epub 2005 Dec 19. FEBS Lett. 2006. PMID: 16380120 Free article. Review.

9

Multiple drugbinding sites on the R482G isoform of the ABCG2 transporter.

Clark R, Kerr ID, Callaghan R. Clark R, et al. Among authors: kerr id. Br J Pharmacol. 2006 Nov;149(5):506-15. doi: 10.1038/sj.bjp.0706904. Epub 2006 Sep 18. Br J Pharmacol. 2006. PMID: 16981002 Free PMC article.

10

Purification and 3D structural analysis of oligomeric human multidrug transporter ABCG2.

McDevitt CA, Collins RF, Conway M, Modok S, Storm J, Kerr ID, Ford RC, Callaghan R. McDevitt CA, et al. Among authors: kerr id. Structure. 2006 Nov;14(11):1623-32. doi: 10.1016/j.str.2006.08.014. Structure. 2006. PMID: 17098188 Free article.

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