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Page 1
The development of MDA-7/IL-24 as a cancer therapeutic.
Dent P, Yacoub A, Hamed HA, Park MA, Dash R, Bhutia SK, Sarkar D, Wang XY, Gupta P, Emdad L, Lebedeva IV, Sauane M, Su ZZ, Rahmani M, Broaddus WC, Young HF, Lesniak MS, Grant S, Curiel DT, Fisher PB. Dent P, et al. Among authors: bhutia sk. Pharmacol Ther. 2010 Nov;128(2):375-84. doi: 10.1016/j.pharmthera.2010.08.001. Epub 2010 Aug 21. Pharmacol Ther. 2010. PMID: 20732354 Free PMC article. Review.
Mechanism by which Mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokine.
Dash R, Richards JE, Su ZZ, Bhutia SK, Azab B, Rahmani M, Dasmahapatra G, Yacoub A, Dent P, Dmitriev IP, Curiel DT, Grant S, Pellecchia M, Reed JC, Sarkar D, Fisher PB. Dash R, et al. Among authors: bhutia sk. Cancer Res. 2010 Jun 15;70(12):5034-45. doi: 10.1158/0008-5472.CAN-10-0563. Epub 2010 May 25. Cancer Res. 2010. PMID: 20501829 Free PMC article.
MDA-7/IL-24 as a cancer therapeutic: from bench to bedside.
Dent P, Yacoub A, Hamed HA, Park MA, Dash R, Bhutia SK, Sarkar D, Gupta P, Emdad L, Lebedeva IV, Sauane M, Su ZZ, Rahmani M, Broaddus WC, Young HF, Lesniak M, Grant S, Curiel DT, Fisher PB. Dent P, et al. Among authors: bhutia sk. Anticancer Drugs. 2010 Sep;21(8):725-31. doi: 10.1097/CAD.0b013e32833cfbe1. Anticancer Drugs. 2010. PMID: 20613485 Free PMC article. Review.
mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.
Dash R, Bhutia SK, Azab B, Su ZZ, Quinn BA, Kegelmen TP, Das SK, Kim K, Lee SG, Park MA, Yacoub A, Rahmani M, Emdad L, Dmitriev IP, Wang XY, Sarkar D, Grant S, Dent P, Curiel DT, Fisher PB. Dash R, et al. Among authors: bhutia sk. Cytokine Growth Factor Rev. 2010 Oct;21(5):381-91. doi: 10.1016/j.cytogfr.2010.08.004. Cytokine Growth Factor Rev. 2010. PMID: 20926331 Free PMC article. Review.
Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells.
Azab B, Dash R, Das SK, Bhutia SK, Shen XN, Quinn BA, Sarkar S, Wang XY, Hedvat M, Dmitriev IP, Curiel DT, Grant S, Dent P, Reed JC, Pellecchia M, Sarkar D, Fisher PB. Azab B, et al. Among authors: bhutia sk. J Cell Physiol. 2012 May;227(5):2145-53. doi: 10.1002/jcp.22947. J Cell Physiol. 2012. PMID: 21780116 Free PMC article.
155 results