Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein.
Noborn F, O'Callaghan P, Hermansson E, Zhang X, Ancsin JB, Damas AM, Dacklin I, Presto J, Johansson J, Saraiva MJ, Lundgren E, Kisilevsky R, Westermark P, Li JP.
Noborn F, et al. Among authors: zhang x.
Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5584-9. doi: 10.1073/pnas.1101194108. Epub 2011 Mar 21.
Proc Natl Acad Sci U S A. 2011.
PMID: 21422279
Free PMC article.