Schreiber SL - Search Results

1

Towards patient-based cancer therapeutics.

Cancer Target Discovery and Development Network; Schreiber SL, Shamji AF, Clemons PA, Hon C, Koehler AN, Munoz B, Palmer M, Stern AM, Wagner BK, Powers S, Lowe SW, Guo X, Krasnitz A, Sawey ET, Sordella R, Stein L, Trotman LC, Califano A, Dalla-Favera R, Ferrando A, Iavarone A, Pasqualucci L, Silva J, Stockwell BR, Hahn WC, Chin L, DePinho RA, Boehm JS, Gopal S, Huang A, Root DE, Weir BA, Gerhard DS, Zenklusen JC, Roth MG, White MA, Minna JD, MacMillan JB, Posner BA. Cancer Target Discovery and Development Network, et al. Among authors: schreiber sl. Nat Biotechnol. 2010 Sep;28(9):904-6. doi: 10.1038/nbt0910-904. Nat Biotechnol. 2010. PMID: 20829823 Free PMC article.

2

Probing the role of homomeric and heteromeric receptor interactions in TGF-beta signaling using small molecule dimerizers.

Stockwell BR, Schreiber SL. Stockwell BR, et al. Among authors: schreiber sl. Curr Biol. 1998 Jun 18;8(13):761-70. doi: 10.1016/s0960-9822(98)70299-4. Curr Biol. 1998. PMID: 9651680 Free article.

3

TGF-beta-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-beta type I receptor fusion proteins.

Stockwell BR, Schreiber SL. Stockwell BR, et al. Among authors: schreiber sl. Chem Biol. 1998 Jul;5(7):385-95. doi: 10.1016/s1074-5521(98)90072-2. Chem Biol. 1998. PMID: 9662508

4

High-throughput screening of small molecules in miniaturized mammalian cell-based assays involving post-translational modifications.

Stockwell BR, Haggarty SJ, Schreiber SL. Stockwell BR, et al. Among authors: schreiber sl. Chem Biol. 1999 Feb;6(2):71-83. doi: 10.1016/S1074-5521(99)80004-0. Chem Biol. 1999. PMID: 10021420

5

Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins.

Hardwick JS, Kuruvilla FG, Tong JK, Shamji AF, Schreiber SL. Hardwick JS, et al. Among authors: schreiber sl. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14866-70. doi: 10.1073/pnas.96.26.14866. Proc Natl Acad Sci U S A. 1999. PMID: 10611304 Free PMC article.

6

Partitioning the transcriptional program induced by rapamycin among the effectors of the Tor proteins.

Shamji AF, Kuruvilla FG, Schreiber SL. Shamji AF, et al. Among authors: schreiber sl. Curr Biol. 2000 Dec 14-28;10(24):1574-81. doi: 10.1016/s0960-9822(00)00866-6. Curr Biol. 2000. PMID: 11137008 Free article.

7

Exploiting site-site interactions on solid support to generate dimeric molecules.

Blackwell HE, Clemons PA, Schreiber SL. Blackwell HE, et al. Among authors: schreiber sl. Org Lett. 2001 Apr 19;3(8):1185-8. doi: 10.1021/ol015647i. Org Lett. 2001. PMID: 11348190

8

Carbon- and nitrogen-quality signaling to translation are mediated by distinct GATA-type transcription factors.

Kuruvilla FG, Shamji AF, Schreiber SL. Kuruvilla FG, et al. Among authors: schreiber sl. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7283-8. doi: 10.1073/pnas.121186898. Proc Natl Acad Sci U S A. 2001. PMID: 11416207 Free PMC article.

9

A one-bead, one-stock solution approach to chemical genetics: part 2.

Clemons PA, Koehler AN, Wagner BK, Sprigings TG, Spring DR, King RW, Schreiber SL, Foley MA. Clemons PA, et al. Among authors: schreiber sl. Chem Biol. 2001 Dec;8(12):1183-95. doi: 10.1016/s1074-5521(01)00086-2. Chem Biol. 2001. PMID: 11755397

10

Synthesis of calcineurin-resistant derivatives of FK506 and selection of compensatory receptors.

Clemons PA, Gladstone BG, Seth A, Chao ED, Foley MA, Schreiber SL. Clemons PA, et al. Among authors: schreiber sl. Chem Biol. 2002 Jan;9(1):49-61. doi: 10.1016/s1074-5521(02)00085-6. Chem Biol. 2002. PMID: 11841938

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