Chen Y - Search Results

1

MT119, a new planar-structured compound, targets the colchicine site of tubulin arresting mitosis and inhibiting tumor cell proliferation.

Zhang Z, Meng T, Yang N, Wang W, Xiong B, Chen Y, Ma L, Shen J, Miao ZH, Ding J. Zhang Z, et al. Among authors: chen y. Int J Cancer. 2011 Jul 1;129(1):214-24. doi: 10.1002/ijc.25661. Epub 2010 Nov 3. Int J Cancer. 2011. PMID: 20830720

2

MCL-1 degradation mediated by JNK activation via MEKK1/TAK1-MKK4 contributes to anticancer activity of new tubulin inhibitor MT189.

Wang W, Wang YQ, Meng T, Yi JM, Huan XJ, Ma LP, Tong LJ, Chen Y, Ding J, Shen JK, Miao ZH. Wang W, et al. Among authors: chen y. Mol Cancer Ther. 2014 Jun;13(6):1480-91. doi: 10.1158/1535-7163.MCT-13-0629. Epub 2014 Mar 31. Mol Cancer Ther. 2014. PMID: 24688049

3

Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide.

Zhou ZL, Luo ZG, Yu B, Jiang Y, Chen Y, Feng JM, Dai M, Tong LJ, Li Z, Li YC, Ding J, Miao ZH. Zhou ZL, et al. Among authors: chen y. Mol Cancer. 2010 Oct 11;9:268. doi: 10.1186/1476-4598-9-268. Mol Cancer. 2010. PMID: 20932347 Free PMC article.

4

PH006, a novel and selective Src kinase inhibitor, suppresses human breast cancer growth and metastasis in vitro and in vivo.

Ma JG, Huang H, Chen SM, Chen Y, Xin XL, Lin LP, Ding J, Liu H, Meng LH. Ma JG, et al. Among authors: chen sm, chen y. Breast Cancer Res Treat. 2011 Nov;130(1):85-96. doi: 10.1007/s10549-010-1302-4. Epub 2010 Dec 22. Breast Cancer Res Treat. 2011. PMID: 21181437

5

Oligomannurarate sulfate sensitizes cancer cells to doxorubicin by inhibiting atypical activation of NF-κB via targeting of Mre11.

Zhang J, Xin X, Chen Q, Xie Z, Gui M, Chen Y, Lin L, Feng J, Li Q, Ding J, Geng M. Zhang J, et al. Among authors: chen q, chen y. Int J Cancer. 2012 Jan 15;130(2):467-77. doi: 10.1002/ijc.26021. Epub 2011 Apr 25. Int J Cancer. 2012. PMID: 21387297

6

Design, synthesis and biological evaluation of substituted 11H-benzo[a]carbazole-5-carboxamides as novel antitumor agents.

Wang YQ, Li XH, He Q, Chen Y, Xie YY, Ding J, Miao ZH, Yang CH. Wang YQ, et al. Among authors: chen y. Eur J Med Chem. 2011 Dec;46(12):5878-84. doi: 10.1016/j.ejmech.2011.09.050. Epub 2011 Oct 4. Eur J Med Chem. 2011. PMID: 22000922

7

Discovery of 3H-imidazo[4,5-b]pyridines as potent c-Met kinase inhibitors: design, synthesis, and biological evaluation.

Chen D, Wang Y, Ma Y, Xiong B, Ai J, Chen Y, Geng M, Shen J. Chen D, et al. Among authors: chen y. ChemMedChem. 2012 Jun;7(6):1057-70. doi: 10.1002/cmdc.201200120. Epub 2012 May 13. ChemMedChem. 2012. PMID: 22581753

8

Characterization of the conversion between CD133+ and CD133- cells in colon cancer SW620 cell line.

Feng JM, Miao ZH, Jiang Y, Chen Y, Li JX, Tong LJ, Zhang J, Huang YR, Ding J. Feng JM, et al. Among authors: chen y. Cancer Biol Ther. 2012 Dec;13(14):1396-406. doi: 10.4161/cbt.22000. Epub 2012 Sep 6. Cancer Biol Ther. 2012. PMID: 22954703 Free PMC article.

9

HSP90 inhibitor AUY922 abrogates up-regulation of RTKs by mTOR inhibitor AZD8055 and potentiates its antiproliferative activity in human breast cancer.

Chen SM, Guo CL, Shi JJ, Xu YC, Chen Y, Shen YY, Su Y, Ding J, Meng LH. Chen SM, et al. Among authors: chen y. Int J Cancer. 2014 Nov 15;135(10):2462-74. doi: 10.1002/ijc.28880. Epub 2014 Apr 17. Int J Cancer. 2014. PMID: 24706460

10

Dual targeting of microtubule and topoisomerase II by α-carboline derivative YCH337 for tumor proliferation and growth inhibition.

Yi JM, Zhang XF, Huan XJ, Song SS, Wang W, Tian QT, Sun YM, Chen Y, Ding J, Wang YQ, Yang CH, Miao ZH. Yi JM, et al. Among authors: chen y. Oncotarget. 2015 Apr 20;6(11):8960-73. doi: 10.18632/oncotarget.3264. Oncotarget. 2015. PMID: 25840421 Free PMC article.

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