Shen J - Search Results

1

MT119, a new planar-structured compound, targets the colchicine site of tubulin arresting mitosis and inhibiting tumor cell proliferation.

Zhang Z, Meng T, Yang N, Wang W, Xiong B, Chen Y, Ma L, Shen J, Miao ZH, Ding J. Zhang Z, et al. Among authors: shen j. Int J Cancer. 2011 Jul 1;129(1):214-24. doi: 10.1002/ijc.25661. Epub 2010 Nov 3. Int J Cancer. 2011. PMID: 20830720

2

Inhibitory mode of 1,5-diarylpyrazole derivatives against cyclooxygenase-2 and cyclooxygenase-1: molecular docking and 3D QSAR analyses.

Liu H, Huang X, Shen J, Luo X, Li M, Xiong B, Chen G, Shen J, Yang Y, Jiang H, Chen K. Liu H, et al. Among authors: shen j. J Med Chem. 2002 Oct 24;45(22):4816-27. doi: 10.1021/jm020089e. J Med Chem. 2002. PMID: 12383007

3

Design, synthesis, and evaluation of Leu*Ala hydroxyethylene-based non-peptide beta-secretase (BACE) inhibitors.

Xiao K, Li X, Li J, Ma L, Hu B, Yu H, Fu Y, Wang R, Ma Z, Qiu B, Li J, Hu D, Wang X, Shen J. Xiao K, et al. Among authors: shen j. Bioorg Med Chem. 2006 Jul 1;14(13):4535-51. doi: 10.1016/j.bmc.2006.02.024. Epub 2006 Feb 28. Bioorg Med Chem. 2006. PMID: 16510290

4

Construction of a small peptide library related to inhibitor OM99-2 and its structure-activity relationship to beta-secretase.

Hu B, Xiong B, Qiu BY, Li X, Yu HP, Xiao K, Wang X, Li J, Shen JK. Hu B, et al. Among authors: shen jk. Acta Pharmacol Sin. 2006 Dec;27(12):1586-93. doi: 10.1111/j.1745-7254.2006.00432.x. Acta Pharmacol Sin. 2006. PMID: 17112413

5

Quinoxalinylurea derivatives as a novel class of JSP-1 inhibitors.

Zhang L, Qiu B, Xiong B, Li X, Li J, Wang X, Li J, Shen J. Zhang L, et al. Among authors: shen j. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2118-22. doi: 10.1016/j.bmcl.2007.01.094. Epub 2007 Feb 2. Bioorg Med Chem Lett. 2007. PMID: 17303416

6

Three-component combinatorial synthesis of a substituted 6H-pyrido[2',1':2,3]imidazo- [4,5-c]isoquinolin-5(6H)-one library with cytotoxic activity.

Meng T, Zhang Z, Hu D, Lin L, Ding J, Wang X, Shen J. Meng T, et al. Among authors: shen j. J Comb Chem. 2007 Sep-Oct;9(5):739-41. doi: 10.1021/cc0700593. Epub 2007 Jun 28. J Comb Chem. 2007. PMID: 17602597 No abstract available.

7

Identification of non-peptidic neuromedin U receptor modulators by a robust homogeneous screening assay.

Meng T, Su HR, Binkert C, Fischli W, Zhou L, Shen JK, Wang MW. Meng T, et al. Acta Pharmacol Sin. 2008 Apr;29(4):517-27. doi: 10.1111/j.1745-7254.2008.00769.x. Acta Pharmacol Sin. 2008. PMID: 18358099

8

Illudalic acid as a potential LAR inhibitor: synthesis, SAR, and preliminary studies on the mechanism of action.

Ling Q, Huang Y, Zhou Y, Cai Z, Xiong B, Zhang Y, Ma L, Wang X, Li X, Li J, Shen J. Ling Q, et al. Among authors: shen j. Bioorg Med Chem. 2008 Aug 1;16(15):7399-409. doi: 10.1016/j.bmc.2008.06.014. Epub 2008 Jun 13. Bioorg Med Chem. 2008. PMID: 18579388

9

Soluble polymer-supported synthesis of 5-arylidene thiazolidinones and pyrimidinones using a novel traceless linker strategy.

Liu Z, Huang Y, Zhang W, Ma L, Li J, Wang X, Li J, Shen J. Liu Z, et al. Among authors: shen j. J Comb Chem. 2008 Sep-Oct;10(5):632-6. doi: 10.1021/cc800054e. Epub 2008 Jul 22. J Comb Chem. 2008. PMID: 18642887

10

DrugViz: a Cytoscape plugin for visualizing and analyzing small molecule drugs in biological networks.

Xiong B, Liu K, Wu J, Burk DL, Jiang H, Shen J. Xiong B, et al. Among authors: shen j. Bioinformatics. 2008 Sep 15;24(18):2117-8. doi: 10.1093/bioinformatics/btn389. Epub 2008 Jul 25. Bioinformatics. 2008. PMID: 18658180

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