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Page 1
Thienopyrimidines as β3-adrenoceptor agonists: hit-to-lead optimization.
Tasler S, Baumgartner R, Ammendola A, Schachtner J, Wieber T, Blisse M, Rath S, Zaja M, Klahn P, Quotschalla U, Ney P. Tasler S, et al. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6108-15. doi: 10.1016/j.bmcl.2010.08.039. Epub 2010 Aug 12. Bioorg Med Chem Lett. 2010. PMID: 20833036
Substituted 2-arylbenzothiazoles as kinase inhibitors: hit-to-lead optimization.
Tasler S, Müller O, Wieber T, Herz T, Pegoraro S, Saeb W, Lang M, Krauss R, Totzke F, Zirrgiebel U, Ehlert JE, Kubbutat MH, Schächtele C. Tasler S, et al. Bioorg Med Chem. 2009 Sep 15;17(18):6728-37. doi: 10.1016/j.bmc.2009.07.047. Epub 2009 Jul 25. Bioorg Med Chem. 2009. PMID: 19692247
A vHTS approach for the identification of beta-adrenoceptor ligands.
Tasler S, Baumgartner R, Aschenbrenner A, Ammendola A, Wolf K, Wieber T, Schachtner J, Blisse M, Quotschalla U, Ney P. Tasler S, et al. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3399-404. doi: 10.1016/j.bmcl.2010.04.009. Epub 2010 Apr 9. Bioorg Med Chem Lett. 2010. PMID: 20434333
Dual binding mode of a novel series of DHODH inhibitors.
Baumgartner R, Walloschek M, Kralik M, Gotschlich A, Tasler S, Mies J, Leban J. Baumgartner R, et al. Among authors: tasler s. J Med Chem. 2006 Feb 23;49(4):1239-47. doi: 10.1021/jm0506975. J Med Chem. 2006. PMID: 16480261
Discovery of 5-HT6 receptor ligands based on virtual HTS.
Tasler S, Kraus J, Wuzik A, Müller O, Aschenbrenner A, Cubero E, Pascual R, Quintana-Ruiz JR, Dordal A, Mercè R, Codony X. Tasler S, et al. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6224-9. doi: 10.1016/j.bmcl.2007.09.016. Epub 2007 Sep 8. Bioorg Med Chem Lett. 2007. PMID: 17892934
Inhibitors of potassium channels KV1.3 and IK-1 as immunosuppressants.
Pegoraro S, Lang M, Dreker T, Kraus J, Hamm S, Meere C, Feurle J, Tasler S, Prütting S, Kuras Z, Visan V, Grissmer S. Pegoraro S, et al. Among authors: tasler s. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2299-304. doi: 10.1016/j.bmcl.2009.02.077. Epub 2009 Feb 25. Bioorg Med Chem Lett. 2009. PMID: 19282171
15 results