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IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance.
Zelante T, De Luca A, Bonifazi P, Montagnoli C, Bozza S, Moretti S, Belladonna ML, Vacca C, Conte C, Mosci P, Bistoni F, Puccetti P, Kastelein RA, Kopf M, Romani L. Zelante T, et al. Among authors: vacca c. Eur J Immunol. 2007 Oct;37(10):2695-706. doi: 10.1002/eji.200737409. Eur J Immunol. 2007. PMID: 17899546 Free article.
IDO mediates TLR9-driven protection from experimental autoimmune diabetes.
Fallarino F, Volpi C, Zelante T, Vacca C, Calvitti M, Fioretti MC, Puccetti P, Romani L, Grohmann U. Fallarino F, et al. Among authors: vacca c. J Immunol. 2009 Nov 15;183(10):6303-12. doi: 10.4049/jimmunol.0901577. Epub 2009 Oct 19. J Immunol. 2009. PMID: 19841163
Th17/Treg imbalance in murine cystic fibrosis is linked to indoleamine 2,3-dioxygenase deficiency but corrected by kynurenines.
Iannitti RG, Carvalho A, Cunha C, De Luca A, Giovannini G, Casagrande A, Zelante T, Vacca C, Fallarino F, Puccetti P, Massi-Benedetti C, Defilippi G, Russo M, Porcaro L, Colombo C, Ratclif L, De Benedictis FM, Romani L. Iannitti RG, et al. Among authors: vacca c. Am J Respir Crit Care Med. 2013 Mar 15;187(6):609-20. doi: 10.1164/rccm.201207-1346OC. Epub 2013 Jan 10. Am J Respir Crit Care Med. 2013. PMID: 23306541
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86.
Orabona C, Grohmann U, Belladonna ML, Fallarino F, Vacca C, Bianchi R, Bozza S, Volpi C, Salomon BL, Fioretti MC, Romani L, Puccetti P. Orabona C, et al. Among authors: vacca c. Nat Immunol. 2004 Nov;5(11):1134-42. doi: 10.1038/ni1124. Epub 2004 Oct 3. Nat Immunol. 2004. PMID: 15467723
Toward the identification of a tolerogenic signature in IDO-competent dendritic cells.
Orabona C, Puccetti P, Vacca C, Bicciato S, Luchini A, Fallarino F, Bianchi R, Velardi E, Perruccio K, Velardi A, Bronte V, Fioretti MC, Grohmann U. Orabona C, et al. Among authors: vacca c. Blood. 2006 Apr 1;107(7):2846-54. doi: 10.1182/blood-2005-10-4077. Epub 2005 Dec 8. Blood. 2006. PMID: 16339401 Free article.
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy.
Grohmann U, Volpi C, Fallarino F, Bozza S, Bianchi R, Vacca C, Orabona C, Belladonna ML, Ayroldi E, Nocentini G, Boon L, Bistoni F, Fioretti MC, Romani L, Riccardi C, Puccetti P. Grohmann U, et al. Among authors: vacca c. Nat Med. 2007 May;13(5):579-86. doi: 10.1038/nm1563. Epub 2007 Apr 8. Nat Med. 2007. PMID: 17417651
324 results