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Research priorities in hypertrophic cardiomyopathy: report of a Working Group of the National Heart, Lung, and Blood Institute.
Force T, Bonow RO, Houser SR, Solaro RJ, Hershberger RE, Adhikari B, Anderson ME, Boineau R, Byrne BJ, Cappola TP, Kalluri R, LeWinter MM, Maron MS, Molkentin JD, Ommen SR, Regnier M, Tang WH, Tian R, Konstam MA, Maron BJ, Seidman CE. Force T, et al. Among authors: molkentin jd. Circulation. 2010 Sep 14;122(11):1130-3. doi: 10.1161/CIRCULATIONAHA.110.950089. Circulation. 2010. PMID: 20837938 Free PMC article. No abstract available.
CaMKII negatively regulates calcineurin-NFAT signaling in cardiac myocytes.
MacDonnell SM, Weisser-Thomas J, Kubo H, Hanscome M, Liu Q, Jaleel N, Berretta R, Chen X, Brown JH, Sabri AK, Molkentin JD, Houser SR. MacDonnell SM, et al. Among authors: molkentin jd. Circ Res. 2009 Aug 14;105(4):316-25. doi: 10.1161/CIRCRESAHA.109.194035. Epub 2009 Jul 16. Circ Res. 2009. PMID: 19608982 Free PMC article.
Enhanced basal contractility but reduced excitation-contraction coupling efficiency and beta-adrenergic reserve of hearts with increased Cav1.2 activity.
Tang M, Zhang X, Li Y, Guan Y, Ai X, Szeto C, Nakayama H, Zhang H, Ge S, Molkentin JD, Houser SR, Chen X. Tang M, et al. Among authors: molkentin jd. Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H519-28. doi: 10.1152/ajpheart.00265.2010. Epub 2010 Jun 11. Am J Physiol Heart Circ Physiol. 2010. PMID: 20543081 Free PMC article.
Increasing cardiac contractility after myocardial infarction exacerbates cardiac injury and pump dysfunction.
Zhang H, Chen X, Gao E, MacDonnell SM, Wang W, Kolpakov M, Nakayama H, Zhang X, Jaleel N, Harris DM, Li Y, Tang M, Berretta R, Leri A, Kajstura J, Sabri A, Koch WJ, Molkentin JD, Houser SR. Zhang H, et al. Among authors: molkentin jd. Circ Res. 2010 Sep 17;107(6):800-9. doi: 10.1161/CIRCRESAHA.110.219220. Epub 2010 Jul 29. Circ Res. 2010. PMID: 20671241 Free PMC article.
Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy.
Chen X, Nakayama H, Zhang X, Ai X, Harris DM, Tang M, Zhang H, Szeto C, Stockbower K, Berretta RM, Eckhart AD, Koch WJ, Molkentin JD, Houser SR. Chen X, et al. Among authors: molkentin jd. J Mol Cell Cardiol. 2011 Mar;50(3):460-70. doi: 10.1016/j.yjmcc.2010.11.012. Epub 2010 Nov 25. J Mol Cell Cardiol. 2011. PMID: 21111744 Free PMC article.
452 results