Hirayama S - Search Results

1

Design and synthesis of KNT-127, a δ-opioid receptor agonist effective by systemic administration.

Nagase H, Nemoto T, Matsubara A, Saito M, Yamamoto N, Osa Y, Hirayama S, Nakajima M, Nakao K, Mochizuki H, Fujii H. Nagase H, et al. Among authors: hirayama s. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6302-5. doi: 10.1016/j.bmcl.2010.08.083. Epub 2010 Aug 21. Bioorg Med Chem Lett. 2010. PMID: 20850307

2

Investigation of Beckett-Casy model 3: synthesis of novel naltrexone derivatives with contracted and expanded D-rings and their pharmacology.

Nagase H, Imaide S, Tomatsu M, Hirayama S, Nemoto T, Sato N, Nakajima M, Nakao K, Mochizuki H, Gouda H, Hirono S, Fujii H. Nagase H, et al. Among authors: hirayama s. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3801-4. doi: 10.1016/j.bmcl.2010.04.044. Epub 2010 Apr 14. Bioorg Med Chem Lett. 2010. PMID: 20478707

3

Synthesis of (-)-homogalanthamine from naltrexone.

Yamamoto N, Fujii H, Imaide S, Hirayama S, Nemoto T, Inokoshi J, Tomoda H, Nagase H. Yamamoto N, et al. Among authors: hirayama s. J Org Chem. 2011 Apr 1;76(7):2257-60. doi: 10.1021/jo1022487. Epub 2011 Mar 7. J Org Chem. 2011. PMID: 21381712

4

Synthesis of novel triplet drugs with 1,3,5-trioxazatriquinane skeletons and their pharmacologies. Part 2: Synthesis of novel triplet drugs with the epoxymethano structure (capped homotriplet).

Nagase H, Koyano K, Wada N, Hirayama S, Watanabe A, Nemoto T, Nakajima M, Nakao K, Mochizuki H, Fujii H. Nagase H, et al. Among authors: hirayama s. Bioorg Med Chem Lett. 2011 Oct 15;21(20):6198-202. doi: 10.1016/j.bmcl.2011.07.065. Epub 2011 Jul 26. Bioorg Med Chem Lett. 2011. PMID: 21889335

5

Usefulness of olanzapine as an adjunct to opioid treatment and for the treatment of neuropathic pain.

Torigoe K, Nakahara K, Rahmadi M, Yoshizawa K, Horiuchi H, Hirayama S, Imai S, Kuzumaki N, Itoh T, Yamashita A, Shakunaga K, Yamasaki M, Nagase H, Matoba M, Suzuki T, Narita M. Torigoe K, et al. Among authors: hirayama s. Anesthesiology. 2012 Jan;116(1):159-69. doi: 10.1097/ALN.0b013e31823c7e56. Anesthesiology. 2012. PMID: 22126917

6

Synthesis of quinolinomorphinan-4-ol derivatives as δ opioid receptor agonists.

Ida Y, Nemoto T, Hirayama S, Fujii H, Osa Y, Imai M, Nakamura T, Kanemasa T, Kato A, Nagase H. Ida Y, et al. Among authors: hirayama s. Bioorg Med Chem. 2012 Jan 15;20(2):949-61. doi: 10.1016/j.bmc.2011.11.047. Epub 2011 Dec 1. Bioorg Med Chem. 2012. PMID: 22197670

7

Effects of mirtazapine on sleep disturbance under neuropathic pain-like state.

Enomoto T, Yamashita A, Torigoe K, Horiuchi H, Hirayama S, Nakahara K, Yanase M, Sakai H, Ikegami D, Nagase H, Suzuki T, Iseki M, Inada E, Narita M. Enomoto T, et al. Among authors: hirayama s. Synapse. 2012 Jun;66(6):483-8. doi: 10.1002/syn.21532. Epub 2012 Feb 24. Synapse. 2012. PMID: 22213404

8

Design and synthesis of novel opioid ligands with an azabicyclo[2.2.2]octane skeleton and their pharmacologies.

Watanabe Y, Kitazawa S, Fujii H, Nemoto T, Hirayama S, Nagase H. Watanabe Y, et al. Among authors: hirayama s. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2689-92. doi: 10.1016/j.bmcl.2012.03.001. Epub 2012 Mar 8. Bioorg Med Chem Lett. 2012. PMID: 22445285

9

Synthesis of new opioid derivatives with a propellane skeleton and their pharmacology. Part 2: Propellane derivatives with an amide side chain.

Nagase H, Akiyama J, Nakajima R, Hirayama S, Nemoto T, Gouda H, Hirono S, Fujii H. Nagase H, et al. Among authors: hirayama s. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2775-9. doi: 10.1016/j.bmcl.2012.02.082. Epub 2012 Mar 2. Bioorg Med Chem Lett. 2012. PMID: 22460026

10

Essential structure of opioid κ receptor agonist nalfurafine for binding to the κ receptor 2: synthesis of decahydro(iminoethano)phenanthrene derivatives and their pharmacologies.

Nagase H, Imaide S, Hirayama S, Nemoto T, Fujii H. Nagase H, et al. Among authors: hirayama s. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5071-4. doi: 10.1016/j.bmcl.2012.05.122. Epub 2012 Jun 7. Bioorg Med Chem Lett. 2012. PMID: 22742909

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