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Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients.
Webb R, Kelly JA, Somers EC, Hughes T, Kaufman KM, Sanchez E, Nath SK, Bruner G, Alarcón-Riquelme ME, Gilkeson GS, Kamen DL, Richardson BC, Harley JB, Sawalha AH. Webb R, et al. Among authors: nath sk. Ann Rheum Dis. 2011 Jan;70(1):151-6. doi: 10.1136/ard.2010.141697. Epub 2010 Sep 29. Ann Rheum Dis. 2011. PMID: 20881011 Free PMC article.
Evidence for a susceptibility gene (SLEH1) on chromosome 11q14 for systemic lupus erythematosus (SLE) families with hemolytic anemia.
Kelly JA, Thompson K, Kilpatrick J, Lam T, Nath SK, Gray-McGuire C, Reid J, Namjou B, Aston CE, Bruner GR, Scofield RH, Harley JB. Kelly JA, et al. Among authors: nath sk. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11766-71. doi: 10.1073/pnas.182162399. Epub 2002 Aug 21. Proc Natl Acad Sci U S A. 2002. PMID: 12192084 Free PMC article.
268 results