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Effect of an antiretroviral regimen containing ritonavir boosted lopinavir on intestinal and hepatic CYP3A, CYP2D6 and P-glycoprotein in HIV-infected patients.
Wyen C, Fuhr U, Frank D, Aarnoutse RE, Klaassen T, Lazar A, Seeringer A, Doroshyenko O, Kirchheiner JC, Abdulrazik F, Schmeisser N, Lehmann C, Hein W, Schömig E, Burger DM, Fätkenheuer G, Jetter A. Wyen C, et al. Among authors: kirchheiner jc. Clin Pharmacol Ther. 2008 Jul;84(1):75-82. doi: 10.1038/sj.clpt.6100452. Epub 2008 Jan 9. Clin Pharmacol Ther. 2008. PMID: 18183034 Free article. Clinical Trial.
Cytochrome P450 2C9 phenotyping using low-dose tolbutamide.
Jetter A, Kinzig-Schippers M, Skott A, Lazar A, Tomalik-Scharte D, Kirchheiner J, Walchner-Bonjean M, Hering U, Jakob V, Rodamer M, Jabrane W, Kasel D, Brockmöller J, Fuhr U, Sörgel F. Jetter A, et al. Among authors: kirchheiner j. Eur J Clin Pharmacol. 2004 May;60(3):165-71. doi: 10.1007/s00228-004-0754-z. Epub 2004 Mar 25. Eur J Clin Pharmacol. 2004. PMID: 15045499
In vivo role of cytochrome P450 2E1 and glutathione-S-transferase activity for acrylamide toxicokinetics in humans.
Doroshyenko O, Fuhr U, Kunz D, Frank D, Kinzig M, Jetter A, Reith Y, Lazar A, Taubert D, Kirchheiner J, Baum M, Eisenbrand G, Berger FI, Bertow D, Berkessel A, Sörgel F, Schömig E, Tomalik-Scharte D. Doroshyenko O, et al. Among authors: kirchheiner j. Cancer Epidemiol Biomarkers Prev. 2009 Feb;18(2):433-43. doi: 10.1158/1055-9965.EPI-08-0832. Epub 2009 Feb 3. Cancer Epidemiol Biomarkers Prev. 2009. PMID: 19190172 Free article.
The role of human CYP2C8 and CYP2C9 variants in pioglitazone metabolism in vitro.
Muschler E, Lal J, Jetter A, Rattay A, Zanger U, Zadoyan G, Fuhr U, Kirchheiner J. Muschler E, et al. Among authors: kirchheiner j. Basic Clin Pharmacol Toxicol. 2009 Dec;105(6):374-9. doi: 10.1111/j.1742-7843.2009.00457.x. Epub 2009 Jul 15. Basic Clin Pharmacol Toxicol. 2009. PMID: 19614891 Free article.
107 results