Walker CL - Search Results

1

Differential localization of ATM is correlated with activation of distinct downstream signaling pathways.

Alexander A, Walker CL. Alexander A, et al. Among authors: walker cl. Cell Cycle. 2010 Sep 15;9(18):3685-6. doi: 10.4161/cc.9.18.13253. Epub 2010 Sep 5. Cell Cycle. 2010. PMID: 20890104 Free PMC article.

2

Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning.

Cai SL, Tee AR, Short JD, Bergeron JM, Kim J, Shen J, Guo R, Johnson CL, Kiguchi K, Walker CL. Cai SL, et al. Among authors: walker cl. J Cell Biol. 2006 Apr 24;173(2):279-89. doi: 10.1083/jcb.200507119. J Cell Biol. 2006. PMID: 16636147 Free PMC article.

3

The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis.

Liang J, Shao SH, Xu ZX, Hennessy B, Ding Z, Larrea M, Kondo S, Dumont DJ, Gutterman JU, Walker CL, Slingerland JM, Mills GB. Liang J, et al. Among authors: walker cl. Nat Cell Biol. 2007 Feb;9(2):218-24. doi: 10.1038/ncb1537. Epub 2007 Jan 21. Nat Cell Biol. 2007. PMID: 17237771

4

Loss of tuberous sclerosis complex-2 function and activation of mammalian target of rapamycin signaling in endometrial carcinoma.

Lu KH, Wu W, Dave B, Slomovitz BM, Burke TW, Munsell MF, Broaddus RR, Walker CL. Lu KH, et al. Among authors: walker cl. Clin Cancer Res. 2008 May 1;14(9):2543-50. doi: 10.1158/1078-0432.CCR-07-0321. Clin Cancer Res. 2008. PMID: 18451215

5

AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.

Short JD, Houston KD, Dere R, Cai SL, Kim J, Johnson CL, Broaddus RR, Shen J, Miyamoto S, Tamanoi F, Kwiatkowski D, Mills GB, Walker CL. Short JD, et al. Among authors: walker cl. Cancer Res. 2008 Aug 15;68(16):6496-506. doi: 10.1158/0008-5472.CAN-07-5756. Cancer Res. 2008. PMID: 18701472 Free PMC article.

6

Cytoplasmic sequestration of p27 via AKT phosphorylation in renal cell carcinoma.

Kim J, Jonasch E, Alexander A, Short JD, Cai S, Wen S, Tsavachidou D, Tamboli P, Czerniak BA, Do KA, Wu KJ, Marlow LA, Wood CG, Copland JA, Walker CL. Kim J, et al. Among authors: walker cl. Clin Cancer Res. 2009 Jan 1;15(1):81-90. doi: 10.1158/1078-0432.CCR-08-0170. Clin Cancer Res. 2009. PMID: 19118035 Free PMC article.

7

PTEN deficiency is fully penetrant for prostate adenocarcinoma in C57BL/6 mice via mTOR-dependent growth.

Blando J, Portis M, Benavides F, Alexander A, Mills G, Dave B, Conti CJ, Kim J, Walker CL. Blando J, et al. Among authors: walker cl. Am J Pathol. 2009 May;174(5):1869-79. doi: 10.2353/ajpath.2009.080055. Am J Pathol. 2009. PMID: 19395652 Free PMC article.

8

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.

Alexander A, Cai SL, Kim J, Nanez A, Sahin M, MacLean KH, Inoki K, Guan KL, Shen J, Person MD, Kusewitt D, Mills GB, Kastan MB, Walker CL. Alexander A, et al. Among authors: walker cl. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4153-8. doi: 10.1073/pnas.0913860107. Epub 2010 Feb 16. Proc Natl Acad Sci U S A. 2010. PMID: 20160076 Free PMC article.

9

Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR.

Dere R, Wilson PD, Sandford RN, Walker CL. Dere R, et al. Among authors: walker cl. PLoS One. 2010 Feb 16;5(2):e9239. doi: 10.1371/journal.pone.0009239. PLoS One. 2010. PMID: 20169078 Free PMC article.

10

ATM engages the TSC2/mTORC1 signaling node to regulate autophagy.

Alexander A, Kim J, Walker CL. Alexander A, et al. Among authors: walker cl. Autophagy. 2010 Jul;6(5):672-3. doi: 10.4161/auto.6.5.12509. Epub 2010 Jul 1. Autophagy. 2010. PMID: 20581436 Free PMC article.

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