Kannan N - Search Results

1

Conformational regulation of the EGFR kinase core by the juxtamembrane and C-terminal tail: a molecular dynamics study.

Mustafa M, Mirza A, Kannan N. Mustafa M, et al. Among authors: kannan n. Proteins. 2011 Jan;79(1):99-114. doi: 10.1002/prot.22862. Epub 2010 Oct 11. Proteins. 2011. PMID: 20938978

2

The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module.

Kannan N, Haste N, Taylor SS, Neuwald AF. Kannan N, et al. Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1272-7. doi: 10.1073/pnas.0610251104. Epub 2007 Jan 16. Proc Natl Acad Sci U S A. 2007. PMID: 17227859 Free PMC article.

3

Co-conserved features associated with cis regulation of ErbB tyrosine kinases.

Mirza A, Mustafa M, Talevich E, Kannan N. Mirza A, et al. Among authors: kannan n. PLoS One. 2010 Dec 13;5(12):e14310. doi: 10.1371/journal.pone.0014310. PLoS One. 2010. PMID: 21179209 Free PMC article.

4

Structural and evolutionary divergence of eukaryotic protein kinases in Apicomplexa.

Talevich E, Mirza A, Kannan N. Talevich E, et al. Among authors: kannan n. BMC Evol Biol. 2011 Nov 2;11:321. doi: 10.1186/1471-2148-11-321. BMC Evol Biol. 2011. PMID: 22047078 Free PMC article.

5

Structural and evolutionary adaptation of rhoptry kinases and pseudokinases, a family of coccidian virulence factors.

Talevich E, Kannan N. Talevich E, et al. Among authors: kannan n. BMC Evol Biol. 2013 Jun 6;13:117. doi: 10.1186/1471-2148-13-117. BMC Evol Biol. 2013. PMID: 23742205 Free PMC article.

6

Kinase regulation by hydrophobic spine assembly in cancer.

Hu J, Ahuja LG, Meharena HS, Kannan N, Kornev AP, Taylor SS, Shaw AS. Hu J, et al. Among authors: kannan n. Mol Cell Biol. 2015 Jan;35(1):264-76. doi: 10.1128/MCB.00943-14. Epub 2014 Oct 27. Mol Cell Biol. 2015. PMID: 25348715 Free PMC article.

7

Inhibiting EGFR dimerization using triazolyl-bridged dimerization arm mimics.

Hanold LE, Oruganty K, Ton NT, Beedle AM, Kannan N, Kennedy EJ. Hanold LE, et al. Among authors: kannan n. PLoS One. 2015 Mar 19;10(3):e0118796. doi: 10.1371/journal.pone.0118796. eCollection 2015. PLoS One. 2015. PMID: 25790232 Free PMC article.

8

Co-conserved MAPK features couple D-domain docking groove to distal allosteric sites via the C-terminal flanking tail.

Nguyen T, Ruan Z, Oruganty K, Kannan N. Nguyen T, et al. Among authors: kannan n. PLoS One. 2015 Mar 23;10(3):e0119636. doi: 10.1371/journal.pone.0119636. eCollection 2015. PLoS One. 2015. PMID: 25799139 Free PMC article.

9

Integration of signaling in the kinome: Architecture and regulation of the αC Helix.

Taylor SS, Shaw AS, Kannan N, Kornev AP. Taylor SS, et al. Among authors: kannan n. Biochim Biophys Acta. 2015 Oct;1854(10 Pt B):1567-74. doi: 10.1016/j.bbapap.2015.04.007. Epub 2015 Apr 17. Biochim Biophys Acta. 2015. PMID: 25891902 Free PMC article.

10

Dialing in EGFR Signaling.

Kennedy EJ, Kannan N. Kennedy EJ, et al. Among authors: kannan n. Chem Biol. 2015 Jun 18;22(6):687-8. doi: 10.1016/j.chembiol.2015.06.001. Chem Biol. 2015. PMID: 26091165

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