Coackley CL - Search Results

1

Tumor cell kill by c-MYC depletion: role of MYC-regulated genes that control DNA double-strand break repair.

Luoto KR, Meng AX, Wasylishen AR, Zhao H, Coackley CL, Penn LZ, Bristow RG. Luoto KR, et al. Among authors: coackley cl. Cancer Res. 2010 Nov 1;70(21):8748-59. doi: 10.1158/0008-5472.CAN-10-0944. Epub 2010 Oct 12. Cancer Res. 2010. PMID: 20940401 Free article.

2

Evidence for the direct binding of phosphorylated p53 to sites of DNA breaks in vivo.

Al Rashid ST, Dellaire G, Cuddihy A, Jalali F, Vaid M, Coackley C, Folkard M, Xu Y, Chen BP, Chen DJ, Lilge L, Prise KM, Bazett Jones DP, Bristow RG. Al Rashid ST, et al. Cancer Res. 2005 Dec 1;65(23):10810-21. doi: 10.1158/0008-5472.CAN-05-0729. Cancer Res. 2005. PMID: 16322227

3

WTp53 induction does not override MTp53 chemoresistance and radioresistance due to gain-of-function in lung cancer cells.

Cuddihy AR, Jalali F, Coackley C, Bristow RG. Cuddihy AR, et al. Mol Cancer Ther. 2008 Apr;7(4):980-92. doi: 10.1158/1535-7163.MCT-07-0471. Mol Cancer Ther. 2008. PMID: 18413811

4

Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment.

Chan N, Pires IM, Bencokova Z, Coackley C, Luoto KR, Bhogal N, Lakshman M, Gottipati P, Oliver FJ, Helleday T, Hammond EM, Bristow RG. Chan N, et al. Cancer Res. 2010 Oct 15;70(20):8045-54. doi: 10.1158/0008-5472.CAN-10-2352. Epub 2010 Oct 5. Cancer Res. 2010. PMID: 20924112 Free PMC article.

5

MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks.

Fraser M, Harding SM, Zhao H, Coackley C, Durocher D, Bristow RG. Fraser M, et al. Cell Cycle. 2011 Jul 1;10(13):2218-32. doi: 10.4161/cc.10.13.16305. Epub 2011 Jul 1. Cell Cycle. 2011. PMID: 21623170

6

PTEN deletion in prostate cancer cells does not associate with loss of RAD51 function: implications for radiotherapy and chemotherapy.

Fraser M, Zhao H, Luoto KR, Lundin C, Coackley C, Chan N, Joshua AM, Bismar TA, Evans A, Helleday T, Bristow RG. Fraser M, et al. Clin Cancer Res. 2012 Feb 15;18(4):1015-27. doi: 10.1158/1078-0432.CCR-11-2189. Epub 2011 Nov 23. Clin Cancer Res. 2012. PMID: 22114138 Free PMC article.

7

Protein-protein interactions occur between p53 phosphoforms and ATM and 53BP1 at sites of exogenous DNA damage.

Al Rashid ST, Harding SM, Law C, Coackley C, Bristow RG. Al Rashid ST, et al. Radiat Res. 2011 May;175(5):588-98. doi: 10.1667/RR2084.1. Epub 2011 Mar 1. Radiat Res. 2011. PMID: 21361779

8

ATM-dependent phosphorylation of 53BP1 in response to genomic stress in oxic and hypoxic cells.

Harding SM, Coackley C, Bristow RG. Harding SM, et al. Radiother Oncol. 2011 Jun;99(3):307-12. doi: 10.1016/j.radonc.2011.05.039. Epub 2011 Jun 15. Radiother Oncol. 2011. PMID: 21680038

9

A novel poly(ADP-ribose) polymerase inhibitor, ABT-888, radiosensitizes malignant human cell lines under hypoxia.

Liu SK, Coackley C, Krause M, Jalali F, Chan N, Bristow RG. Liu SK, et al. Radiother Oncol. 2008 Aug;88(2):258-68. doi: 10.1016/j.radonc.2008.04.005. Epub 2008 May 2. Radiother Oncol. 2008. PMID: 18456354

10

In vivo studies of the PARP inhibitor, AZD-2281, in combination with fractionated radiotherapy: An exploration of the therapeutic ratio.

Gani C, Coackley C, Kumareswaran R, Schütze C, Krause M, Zafarana G, Bristow RG. Gani C, et al. Radiother Oncol. 2015 Sep;116(3):486-94. doi: 10.1016/j.radonc.2015.08.003. Epub 2015 Aug 12. Radiother Oncol. 2015. PMID: 26277432

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