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ProHits: integrated software for mass spectrometry-based interaction proteomics.
Liu G, Zhang J, Larsen B, Stark C, Breitkreutz A, Lin ZY, Breitkreutz BJ, Ding Y, Colwill K, Pasculescu A, Pawson T, Wrana JL, Nesvizhskii AI, Raught B, Tyers M, Gingras AC. Liu G, et al. Among authors: wrana jl. Nat Biotechnol. 2010 Oct;28(10):1015-7. doi: 10.1038/nbt1010-1015. Nat Biotechnol. 2010. PMID: 20944583 Free PMC article. No abstract available.
Signal transduction. Mad about SMADs.
Wrana J, Pawson T. Wrana J, et al. Nature. 1997 Jul 3;388(6637):28-9. doi: 10.1038/40290. Nature. 1997. PMID: 9214496 No abstract available.
An experimentally derived confidence score for binary protein-protein interactions.
Braun P, Tasan M, Dreze M, Barrios-Rodiles M, Lemmens I, Yu H, Sahalie JM, Murray RR, Roncari L, de Smet AS, Venkatesan K, Rual JF, Vandenhaute J, Cusick ME, Pawson T, Hill DE, Tavernier J, Wrana JL, Roth FP, Vidal M. Braun P, et al. Among authors: wrana jl. Nat Methods. 2009 Jan;6(1):91-7. doi: 10.1038/nmeth.1281. Epub 2008 Dec 7. Nat Methods. 2009. PMID: 19060903 Free PMC article.
Functional characterization of a PROTAC directed against BRAF mutant V600E.
Posternak G, Tang X, Maisonneuve P, Jin T, Lavoie H, Daou S, Orlicky S, Goullet de Rugy T, Caldwell L, Chan K, Aman A, Prakesch M, Poda G, Mader P, Wong C, Maier S, Kitaygorodsky J, Larsen B, Colwill K, Yin Z, Ceccarelli DF, Batey RA, Taipale M, Kurinov I, Uehling D, Wrana J, Durocher D, Gingras AC, Al-Awar R, Therrien M, Sicheri F. Posternak G, et al. Nat Chem Biol. 2020 Nov;16(11):1170-1178. doi: 10.1038/s41589-020-0609-7. Epub 2020 Aug 10. Nat Chem Biol. 2020. PMID: 32778845 Free PMC article.
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.
So J, Pasculescu A, Dai AY, Williton K, James A, Nguyen V, Creixell P, Schoof EM, Sinclair J, Barrios-Rodiles M, Gu J, Krizus A, Williams R, Olhovsky M, Dennis JW, Wrana JL, Linding R, Jorgensen C, Pawson T, Colwill K. So J, et al. Among authors: wrana jl. Sci Signal. 2015 Apr 7;8(371):rs3. doi: 10.1126/scisignal.2005700. Sci Signal. 2015. PMID: 25852190
A feed forward loop enforces YAP/TAZ signaling during tumorigenesis.
Gill MK, Christova T, Zhang YY, Gregorieff A, Zhang L, Narimatsu M, Song S, Xiong S, Couzens AL, Tong J, Krieger JR, Moran MF, Zlotta AR, van der Kwast TH, Gingras AC, Sicheri F, Wrana JL, Attisano L. Gill MK, et al. Among authors: wrana jl. Nat Commun. 2018 Aug 29;9(1):3510. doi: 10.1038/s41467-018-05939-2. Nat Commun. 2018. PMID: 30158528 Free PMC article.
291 results