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Page 1
cis-Regulatory remodeling of the SCL locus during vertebrate evolution.
Göttgens B, Ferreira R, Sanchez MJ, Ishibashi S, Li J, Spensberger D, Lefevre P, Ottersbach K, Chapman M, Kinston S, Knezevic K, Hoogenkamp M, Follows GA, Bonifer C, Amaya E, Green AR. Göttgens B, et al. Among authors: ottersbach k. Mol Cell Biol. 2010 Dec;30(24):5741-51. doi: 10.1128/MCB.00870-10. Epub 2010 Oct 18. Mol Cell Biol. 2010. PMID: 20956563 Free PMC article.
Gfi1 expression is controlled by five distinct regulatory regions spread over 100 kilobases, with Scl/Tal1, Gata2, PU.1, Erg, Meis1, and Runx1 acting as upstream regulators in early hematopoietic cells.
Wilson NK, Timms RT, Kinston SJ, Cheng YH, Oram SH, Landry JR, Mullender J, Ottersbach K, Gottgens B. Wilson NK, et al. Among authors: ottersbach k. Mol Cell Biol. 2010 Aug;30(15):3853-63. doi: 10.1128/MCB.00032-10. Epub 2010 Jun 1. Mol Cell Biol. 2010. PMID: 20516218 Free PMC article.
Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development.
Pimanda JE, Ottersbach K, Knezevic K, Kinston S, Chan WY, Wilson NK, Landry JR, Wood AD, Kolb-Kokocinski A, Green AR, Tannahill D, Lacaud G, Kouskoff V, Göttgens B. Pimanda JE, et al. Among authors: ottersbach k. Proc Natl Acad Sci U S A. 2007 Nov 6;104(45):17692-7. doi: 10.1073/pnas.0707045104. Epub 2007 Oct 25. Proc Natl Acad Sci U S A. 2007. PMID: 17962413 Free PMC article.
Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver.
Landry JR, Kinston S, Knezevic K, de Bruijn MF, Wilson N, Nottingham WT, Peitz M, Edenhofer F, Pimanda JE, Ottersbach K, Göttgens B. Landry JR, et al. Among authors: ottersbach k. Blood. 2008 Mar 15;111(6):3005-14. doi: 10.1182/blood-2007-07-098830. Epub 2008 Jan 9. Blood. 2008. PMID: 18184866 Free article.
Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.
Tijssen MR, Cvejic A, Joshi A, Hannah RL, Ferreira R, Forrai A, Bellissimo DC, Oram SH, Smethurst PA, Wilson NK, Wang X, Ottersbach K, Stemple DL, Green AR, Ouwehand WH, Göttgens B. Tijssen MR, et al. Among authors: ottersbach k. Dev Cell. 2011 May 17;20(5):597-609. doi: 10.1016/j.devcel.2011.04.008. Dev Cell. 2011. PMID: 21571218 Free PMC article.
A Runx1-Smad6 rheostat controls Runx1 activity during embryonic hematopoiesis.
Knezevic K, Bee T, Wilson NK, Janes ME, Kinston S, Polderdijk S, Kolb-Kokocinski A, Ottersbach K, Pencovich N, Groner Y, de Bruijn M, Göttgens B, Pimanda JE. Knezevic K, et al. Among authors: ottersbach k. Mol Cell Biol. 2011 Jul;31(14):2817-26. doi: 10.1128/MCB.01305-10. Epub 2011 May 16. Mol Cell Biol. 2011. PMID: 21576367 Free PMC article.
SMAD1 and SMAD5 Expression Is Coordinately Regulated by FLI1 and GATA2 during Endothelial Development.
Marks-Bluth J, Khanna A, Chandrakanthan V, Thoms J, Bee T, Eich C, Kang YC, Knezevic K, Qiao Q, Fitch S, Oxburgh L, Ottersbach K, Dzierzak E, de Bruijn MF, Pimanda JE. Marks-Bluth J, et al. Among authors: ottersbach k. Mol Cell Biol. 2015 Jun;35(12):2165-72. doi: 10.1128/MCB.00239-15. Epub 2015 Apr 13. Mol Cell Biol. 2015. PMID: 25870111 Free PMC article.
Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code.
Pimanda JE, Chan WY, Wilson NK, Smith AM, Kinston S, Knezevic K, Janes ME, Landry JR, Kolb-Kokocinski A, Frampton J, Tannahill D, Ottersbach K, Follows GA, Lacaud G, Kouskoff V, Göttgens B. Pimanda JE, et al. Among authors: ottersbach k. Blood. 2008 Dec 1;112(12):4512-22. doi: 10.1182/blood-2008-05-157560. Epub 2008 Sep 19. Blood. 2008. PMID: 18805961 Free PMC article.
Ontogeny of haematopoiesis: recent advances and open questions.
Ottersbach K, Smith A, Wood A, Göttgens B. Ottersbach K, et al. Br J Haematol. 2010 Feb;148(3):343-55. doi: 10.1111/j.1365-2141.2009.07953.x. Epub 2009 Oct 22. Br J Haematol. 2010. PMID: 19863543 Free article. Review.
56 results